A fully orthogonal system for protein synthesis in bacterial cells

par Nikolay A. Aleksashin, Teresa Szal, Anne E. d’Aquino, Michael C. Jewett, Nora Vázquez-Laslop, Alexander S. Mankin
Publié 2020

Assembly and functionality of the ribosome with tethered subunits

par Nikolay A. Aleksashin, Margus Leppik, Adam J. Hockenberry, Dorota Klepacki, Nora Vázquez-Laslop, Michael C. Jewett, Jaanus Remme, Alexander S. Mankin
Publié 2019

Engineered ribosomes with tethered subunits for expanding biological function

par Erik D. Carlson, Anne E. d’Aquino, Do Soon Kim, Emily M. Fulk, Kim Hoang, Teresa Szal, Alexander S. Mankin, Michael C. Jewett
Publié 2019

Context-specific action of macrolide antibiotics on the eukaryotic ribosome

par Maxim S. Svetlov, Timm O. Koller, Sezen Meydan, Vaishnavi Shankar, Dorota Klepacki, Norbert Polacek, Nicholas R. Guydosh, Nora Vázquez-Laslop, Daniel N. Wilson, Alexander S. Mankin
Publié 2021

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

par Shijie Huang, Nikolay A. Aleksashin, Anna B. Loveland, Dorota Klepacki, Kaspar Reier, Amira Kefi, Teresa Szal, Jaanus Remme, Luc Jaeger, Nora Vázquez-Laslop, Andrei A. Korostelev, Alexander S. Mankin
Publié 2020

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

par Bertrand Beckert, Elodie C. Leroy, Shanmugapriya Sothiselvam, Lars V. Bock, Maxim S. Svetlov, Michael Graf, Stefan Arenz, Maha Abdelshahid, Britta Seip, Helmut Grubmüller, Alexander S. Mankin, C. Axel Innis, Nora Vázquez-Laslop, Daniel N. Wilson
Publié 2021