Vaccines for human fungal diseases: close but still a long way to go

by Lorena V. N. Oliveira, Ruiying Wang, Charles A. Specht, Stuart M. Levitz
Published 2021

A Glycosylphosphatidylinositol Anchor Is Required for Membrane Localization but Dispensable for Cell Wall Association of Chitin Deacetylase 2 in <named-content content-type="genus-...

by Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, Jennifer K. Lodge
Published 2012

Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded β-Glucan Particles

by Haibin Huang, Gary R. Ostroff, Chrono K. Lee, Charles A. Specht, Stuart M. Levitz
Published 2010

Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of <named-content content-type="genus-species">Cryptococcus neoforman...

by Rajendra Upadhya, Woei C. Lam, Brian Maybruck, Charles A. Specht, Stuart M. Levitz, Jennifer K. Lodge
Published 2016

<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

by Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, Jennifer K. Lodge
Published 2018

The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in <named-content content-type="genus-species">Cryptococcus neofor...

by Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma. Xenia G. Ilagan, Maureen J. Donlin, Jennifer K. Lodge
Published 2019

Linkage Specificity and Role of Properdin in Activation of the Alternative Complement Pathway by Fungal Glycans

by Sarika Agarwal, Charles A. Specht, Haibin Huang, Gary R. Ostroff, Sanjay Ram, Peter A. Rice, Stuart M. Levitz
Published 2011

Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production.

by Bhawna Yadav, Charles A Specht, Chrono K Lee, Maria Pokrovskii, Jun R Huh, Dan R Littman, Stuart M Levitz
Published 2021

Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen <named-content content-type="genus-species">Cryptococcus gattii</named-content>

by Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, Jennifer K. Lodge
Published 2019

Cross Talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A Pathways in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

by Maureen J. Donlin, Rajendra Upadhya, Kimberly J. Gerik, Woei Lam, Laura G. VanArendonk, Charles A. Specht, Neil K. Sharma, Jennifer K. Lodge
Published 2014

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing <italic toggle="yes">Cryptococcus</italic> Alkaline Extracts

by Charles A. Specht, Chrono K. Lee, Haibin Huang, Donald J. Tipper, Zu T. Shen, Jennifer K. Lodge, John Leszyk, Gary R. Ostroff, Stuart M. Levitz
Published 2015

Vaccination with Recombinant <italic toggle="yes">Cryptococcus</italic> Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain an...

by Charles A. Specht, Chrono K. Lee, Haibin Huang, Maureen M. Hester, Jianhua Liu, Bridget A. Luckie, Melanie A. Torres Santana, Zeynep Mirza, Payam Khoshkenar, Ambily Abraham, Zu T. Shen, Jennifer K. Lodge, Ali Akalin, Jane Homan, Gary R. Ostroff, Stuart M. Levitz
Published 2017