Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs

by Hatice U. Osmanbeyoglu, Eneda Toska, Carmen Chan, José Baselga, Christina S. Leslie
Published 2017

HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP

by Merve Sahin, Wilfred Wong, Yingqian Zhan, Kinsey Van Deynze, Richard Koche, Christina S. Leslie
Published 2021

An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data

by Mark Carty, Lee Zamparo, Merve Sahin, Alvaro González, Raphael Pelossof, Olivier Elemento, Christina S. Leslie
Published 2017

Ets transcription factor GABP controls T cell homeostasis and immunity

by Chong T. Luo, Hatice U. Osmanbeyoglu, Mytrang H. Do, Michael R. Bivona, Ahmed Toure, Davina Kang, Yuchen Xie, Christina S. Leslie, Ming O. Li
Published 2017

Widespread intronic polyadenylation diversifies immune cell transcriptomes

by Irtisha Singh, Shih-Han Lee, Adam S. Sperling, Mehmet K. Samur, Yu-Tzu Tai, Mariateresa Fulciniti, Nikhil C. Munshi, Christine Mayr, Christina S. Leslie
Published 2018

Cytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation.

by Saritha Suram, Lori J Silveira, Spencer Mahaffey, Gordon D Brown, Joseph V Bonventre, David L Williams, Neil A R Gow, Donna L Bratton, Robert C Murphy, Christina C Leslie
Published 2013

Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.

by Enrica San Pietro, Mariagrazia Capestrano, Elena V Polishchuk, Alessio DiPentima, Alvar Trucco, Pasquale Zizza, Stefania Mariggiò, Teodoro Pulvirenti, Michele Sallese, Stefano Tete, Alexander A Mironov, Christina C Leslie, Daniela Corda, Alberto Luini, Roman S Polishchuk
Published 2009

Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers

by Hatice U. Osmanbeyoglu, Fumiko Shimizu, Angela Rynne-Vidal, Direna Alonso-Curbelo, Hsuan-An Chen, Hannah Y. Wen, Tsz-Lun Yeung, Petar Jelinic, Pedram Razavi, Scott W. Lowe, Samuel C. Mok, Gabriela Chiosis, Douglas A. Levine, Christina S. Leslie
Published 2019

HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells

by Diu T. T. Nguyen, Yuheng Lu, Karen L. Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R. Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M. Savino, Saroj Gourkanti, Payal Patel, Ly P. Vu, Christina S. Leslie, Michael G. Kharas
Published 2020

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

by Gerard Minuesa, Steven K. Albanese, Wei Xie, Yaniv Kazansky, Daniel Worroll, Arthur Chow, Alexandra Schurer, Sun-Mi Park, Christina Z. Rotsides, James Taggart, Andrea Rizzi, Levi N. Naden, Timothy Chou, Saroj Gourkanti, Daniel Cappel, Maria C. Passarelli, Lauren Fairchild, Carolina Adura, J. Fraser Glickman, Jessica Schulman, Christopher Famulare, Minal Patel, Joseph K. Eibl, Gregory M. Ross, Shibani Bhattacharya, Derek S. Tan, Christina S. Leslie, Thijs Beuming, Dinshaw J. Patel, Yehuda Goldgur, John D. Chodera, Michael G. Kharas
Published 2019