Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH)

par David M. Wilson, David M. Wilson, Matthew A. J. Duncton, Caleb Chang, Christie Lee Luo, Taxiarchis M. Georgiadis, Patricia Pellicena, Ashley M. Deacon, Yang Gao, Debanu Das
Publié 2021

Androgen receptor-binding sites are highly mutated in prostate cancer

par Tunç Morova, Daniel R. McNeill, Nada Lallous, Mehmet Gönen, Kush Dalal, David M. Wilson, Attila Gürsoy, Özlem Keskin, Nathan A. Lack
Publié 2020

Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.

par Mamta D Naidu, Rakhi Agarwal, Louis A Pena, Luis Cunha, Mihaly Mezei, Min Shen, David M Wilson, Yuan Liu, Zina Sanchez, Pankaj Chaudhary, Samuel H Wilson, Michael J Waring
Publié 2011

Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers

par Kiel D. Neumann, Javier E. Villanueva-Meyer, Christopher A. Mutch, Robert R. Flavell, Joseph E. Blecha, Tiffany Kwak, Renuka Sriram, Henry F. VanBrocklin, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson
Publié 2017

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

par Sanju Sinha, Karina Barbosa, Kuoyuan Cheng, Mark D. M. Leiserson, Prashant Jain, Anagha Deshpande, David M. Wilson, Bríd M. Ryan, Ji Luo, Ze’ev A. Ronai, Joo Sang Lee, Aniruddha J. Deshpande, Eytan Ruppin
Publié 2021

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

par Adriana E. Tron, Matthew A. Belmonte, Ammar Adam, Brian M. Aquila, Lawrence H. Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J. Embrey, Eric Gangl, Francis D. Gibbons, Gareth P. Gregory, David Hargreaves, J. Adam Hendricks, Jeffrey W. Johannes, Ricky W. Johnstone, Steven L. Kazmirski, Jason G. Kettle, Michelle L. Lamb, Shannon M. Matulis, Ajay K. Nooka, Martin J. Packer, Bo Peng, Philip B. Rawlins, Daniel W. Robbins, Alwin G. Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J. Paul Secrist, Edwin A. Clark, David M. Wilson, Stephen E. Fawell, Alexander W. Hird
Publié 2018