A dynamical systems model for combinatorial cancer therapy enhances oncolytic adenovirus efficacy by MEK-inhibition.

par Neda Bagheri, Marisa Shiina, Douglas A Lauffenburger, W Michael Korn
Publié 2011

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

par Lauren E. Stopfer, Joshua M. Mesfin, Brian A. Joughin, Douglas A. Lauffenburger, Forest M. White
Publié 2020

Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli.

par Melody K Morris, Julio Saez-Rodriguez, David C Clarke, Peter K Sorger, Douglas A Lauffenburger
Publié 2011

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.

par Bree B Aldridge, Julio Saez-Rodriguez, Jeremy L Muhlich, Peter K Sorger, Douglas A Lauffenburger
Publié 2009

Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-α-induced apoptosis in the intestinal epithelium.

par Ken S Lau, Virna Cortez-Retamozo, Sarah R Philips, Mikael J Pittet, Douglas A Lauffenburger, Kevin M Haigis
Publié 2012

In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

par Gaurav Luthria, Ran Li, Stephanie Wang, Mark Prytyskach, Rainer H. Kohler, Douglas A. Lauffenburger, Timothy J. Mitchison, Ralph Weissleder, Miles A. Miller
Publié 2020

Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation

par Lucia Suarez-Lopez, Bing Shui, Douglas K. Brubaker, Marza Hill, Alexander Bergendorf, Paul S. Changelian, Aisha Laguna, Alina Starchenko, Douglas A. Lauffenburger, Kevin M. Haigis
Publié 2021

Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features

par Yannic C. Bartsch, Carolin Loos, Evan Rossignol, Jesse M. Fajnzylber, Dansu Yuan, Anchalee Avihingsanon, Sasiwimol Ubolyam, Thidarat Jupimai, Bernard Hirschel, Jintanat Ananworanich, Douglas A. Lauffenburger, Jonathan Z. Li, Galit Alter, Boris Julg
Publié 2021

Discrete SARS-CoV-2 antibody titers track with functional humoral stability

par Yannic C. Bartsch, Stephanie Fischinger, Sameed M. Siddiqui, Zhilin Chen, Jingyou Yu, Makda Gebre, Caroline Atyeo, Matthew J. Gorman, Alex Lee Zhu, Jaewon Kang, John S. Burke, Matthew Slein, Matthew J. Gluck, Samuel Beger, Yiyuan Hu, Justin Rhee, Eric Petersen, Benjamin Mormann, Michael de St Aubin, Mohammad A. Hasdianda, Guruprasad Jambaulikar, Edward W. Boyer, Pardis C. Sabeti, Dan H. Barouch, Boris D. Julg, Elon R. Musk, Anil S. Menon, Douglas A. Lauffenburger, Eric J. Nilles, Galit Alter
Publié 2021

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

par Elizabeth C. Randall, Kristina B. Emdal, Janice K. Laramy, Minjee Kim, Alison Roos, David Calligaris, Michael S. Regan, Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Aaron J. Johnson, Fa-Ke Lu, X. Sunney Xie, Brian A. Joughin, Raven J. Reddy, Sen Peng, Walid M. Abdelmoula, Pamela R. Jackson, Aarti Kolluri, Katherine A. Kellersberger, Jeffrey N. Agar, Douglas A. Lauffenburger, Kristin R. Swanson, Nhan L. Tran, William F. Elmquist, Forest M. White, Jann N. Sarkaria, Nathalie Y. R. Agar
Publié 2018

Epidemiological and Immunological Features of Obesity and SARS-CoV-2

par Eric J. Nilles, Sameed M. Siddiqui, Stephanie Fischinger, Yannic C. Bartsch, Michael de St. Aubin, Guohai Zhou, Matthew J. Gluck, Samuel Berger, Justin Rhee, Eric Petersen, Benjamin Mormann, Michael Loesche, Yiyuan Hu, Zhilin Chen, Jingyou Yu, Makda Gebre, Caroline Atyeo, Matthew J. Gorman, Alex Lee Zhu, John Burke, Matthew Slein, Mohammad A. Hasdianda, Guruprasad Jambaulikar, Edward W. Boyer, Pardis C. Sabeti, Dan H. Barouch, Boris Julg, Adam J. Kucharski, Elon R. Musk, Douglas A. Lauffenburger, Galit Alter, Anil S. Menon
Publié 2021