List of Agents of S.H.I.E.L.D. characters

The series stars Clark Gregg, reprising his role of Phil Coulson from the films, as well as Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, and Elizabeth Henstridge. Nick Blood and Adrianne Palicki joined the cast for the second and third seasons, while Henry Simmons and Luke Mitchell had recurring roles in the second season before being promoted to the main cast for the third. John Hannah, who recurred in the third season, joined the main cast in the fourth, while Natalia Cordova-Buckley, who recurred in both the third and fourth seasons, was promoted to the main cast for the series' fifth season. Jeff Ward was promoted to the main cast for the sixth season after recurring in the fifth. Additionally, some characters from Marvel Cinematic Universe films and Marvel One-Shots also appear throughout the series, along with other characters based on various Marvel Comics properties. Several characters from the series also appear in the supplemental digital series ''Agents of S.H.I.E.L.D.: Slingshot''.
This list includes the series' main cast, all guest stars deemed to have had recurring roles throughout the series, and any other guest who is otherwise notable.
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4p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradationby Bárbara González-Terán, Juan Antonio López, Elena Rodríguez, Luis Leiva, Sara Martínez-Martínez, Juan Antonio Bernal, Luis Jesús Jiménez-Borreguero, Juan Miguel Redondo, Jesús Vazquez, Guadalupe SabioGet full text
Published 2016
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5by Celia de la Calle Arregui, Ana Belén Plata-Gómez, Nerea Deleyto-Seldas, Fernando García, Ana Ortega-Molina, Julio Abril-Garrido, Elena Rodriguez, Ivan Nemazanyy, Laura Tribouillard, Alba de Martino, Eduardo Caleiras, Ramón Campos-Olivas, Francisca Mulero, Mathieu Laplante, Javier Muñoz, Mario Pende, Guadalupe Sabio, David M. Sabatini, Alejo EfeyanGet full text
Published 2021
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6by Nuria Matesanz, Edgar Bernardo, Rebeca Acín-Pérez, Elisa Manieri, Sonia Pérez-Sieira, Lourdes Hernández-Cosido, Valle Montalvo-Romeral, Alfonso Mora, Elena Rodríguez, Luis Leiva-Vega, Ana Victoria Lechuga-Vieco, Jesús Ruiz-Cabello, Jorge L. Torres, Maria Crespo-Ruiz, Francisco Centeno, Clara V. Álvarez, Miguel Marcos, Jose Antonio Enríquez, Ruben Nogueiras, Guadalupe SabioGet full text
Published 2017
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7by Ayelén M Santamans, Valle Montalvo-Romeral, Alfonso Mora, Juan Antonio Lopez, Francisco González-Romero, Daniel Jimenez-Blasco, Elena Rodríguez, Aránzazu Pintor-Chocano, Cristina Casanueva-Benítez, Rebeca Acín-Pérez, Luis Leiva-Vega, Jordi Duran, Joan J Guinovart, Jesús Jiménez-Borreguero, José Antonio Enríquez, María Villlalba-Orero, Juan P Bolaños, Patricia Aspichueta, Jesús Vázquez, Bárbara González-Terán, Guadalupe SabioGet full text
Published 2021
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