Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.

par Kevin M Brown, Elena Suvorova, Andrew Farrell, Aaron McLain, Ashley Dittmar, Graham B Wiley, Gabor Marth, Patrick M Gaffney, Marc Jan Gubbels, Michael White, Ira J Blader
Publié 2014

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks

par Richard C. Pelikan, Jennifer A. Kelly, Yao Fu, Caleb A. Lareau, Kandice L. Tessneer, Graham B. Wiley, Mandi M. Wiley, Stuart B. Glenn, John B. Harley, Joel M. Guthridge, Judith A. James, Martin J. Aryee, Courtney Montgomery, Patrick M. Gaffney
Publié 2018