The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing

par Xiaohui Hu, Samuel E. Harvey, Rong Zheng, Jingyi Lyu, Caitlin L. Grzeskowiak, Emily Powell, Helen Piwnica-Worms, Kenneth L. Scott, Chonghui Cheng
Publié 2020

The cytosolic iron–sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors

par Abena B. Redwood, Xiaomei Zhang, Sahil B. Seth, Zhongqi Ge, Wendy E. Bindeman, Xinhui Zhou, Vidya C. Sinha, Timothy P. Heffernan, Helen Piwnica-Worms
Publié 2021

Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast

par Vidya C. Sinha, Amanda L. Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A. Zebala, Dean Y. Maeda, Florencia McAllister, Helen Piwnica-Worms
Publié 2021

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

par Gloria V. Echeverria, Emily Powell, Sahil Seth, Zhongqi Ge, Alessandro Carugo, Christopher Bristow, Michael Peoples, Frederick Robinson, Huan Qiu, Jiansu Shao, Sabrina L. Jeter-Jones, Xiaomei Zhang, Vandhana Ramamoorthy, Shirong Cai, Wenhui Wu, Giulio Draetta, Stacy L. Moulder, William F. Symmans, Jeffrey T. Chang, Timothy P. Heffernan, Helen Piwnica-Worms
Publié 2018

HIF2 Regulates Intestinal Wnt5a Expression

par Carolina J. García García, Carolina J. García García, Carolina J. García García, Carolina J. García García, Ariana C. Acevedo Diaz, Neeraj Kumari, Neeraj Kumari, Suman Govindaraju, Marimar de la Cruz Bonilla, Marimar de la Cruz Bonilla, Marimar de la Cruz Bonilla, F. Anthony San Lucas, Nicholas D. Nguyen, Nicholas D. Nguyen, Iancarlos Jiménez Sacarello, Helen Piwnica-Worms, Anirban Maitra, Cullen M. Taniguchi, Cullen M. Taniguchi
Publié 2021

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

par Vrutant V. Shah, Aundrietta D. Duncan, Shiming Jiang, Sabrina A. Stratton, Kendra L. Allton, Clinton Yam, Abhinav Jain, Patrick M. Krause, Yue Lu, Shirong Cai, Yizheng Tu, Xinhui Zhou, Xiaomei Zhang, Yan Jiang, Christopher L. Carroll, Zhijun Kang, Bin Liu, Jianjun Shen, Mihai Gagea, Sebastian M. Manu, Lei Huo, Michael Gilcrease, Reid T. Powell, Lei Guo, Clifford Stephan, Peter J. Davies, Jan Parker-Thornburg, Guillermina Lozano, Richard R. Behringer, Helen Piwnica-Worms, Jeffrey T. Chang, Stacy L. Moulder, Michelle Craig Barton
Publié 2021