Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function.

par David C Bersten, John B Bruning, Daniel J Peet, Murray L Whitelaw
Publié 2014

Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia

par Charlotte E. J. Downes, Barbara J. McClure, John B. Bruning, Elyse Page, James Breen, Jacqueline Rehn, David T. Yeung, Deborah L. White
Publié 2021

HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

par Jie Zheng, Mi Ra Chang, Ryan E. Stites, Yong Wang, John B. Bruning, Bruce D. Pascal, Scott J. Novick, Ruben D. Garcia-Ordonez, Keith R. Stayrook, Michael J. Chalmers, Jeffrey A. Dodge, Patrick R. Griffin
Publié 2017