Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction

par Linda Kachuri, Rebecca E. Graff, Karl Smith-Byrne, Travis J. Meyers, Sara R. Rashkin, Elad Ziv, John S. Witte, Mattias Johansson
Publié 2020

Author Correction: Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms

par Nima C. Emami, Linda Kachuri, Travis J. Meyers, Rajdeep Das, Joshua D. Hoffman, Thomas J. Hoffmann, Donglei Hu, Jun Shan, Felix Y. Feng, Elad Ziv, Stephen K. Van Den Eeden, John S. Witte
Publié 2019

Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms

par Nima C. Emami, Linda Kachuri, Travis J. Meyers, Rajdeep Das, Joshua D. Hoffman, Thomas J. Hoffmann, Donglei Hu, Jun Shan, Felix Y. Feng, Elad Ziv, Stephen K. Van Den Eeden, John S. Witte
Publié 2019

Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

par Sara R. Rashkin, Rebecca E. Graff, Linda Kachuri, Khanh K. Thai, Stacey E. Alexeeff, Maruta A. Blatchins, Taylor B. Cavazos, Douglas A. Corley, Nima C. Emami, Joshua D. Hoffman, Eric Jorgenson, Lawrence H. Kushi, Travis J. Meyers, Stephen K. Van Den Eeden, Elad Ziv, Laurel A. Habel, Thomas J. Hoffmann, Lori C. Sakoda, John S. Witte
Publié 2020

Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

par Rebecca E. Graff, Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua D. Hoffman, Stacey E. Alexeeff, Maruta Blatchins, Travis J. Meyers, Lancelote Leong, Caroline G. Tai, Nima C. Emami, Douglas A. Corley, Lawrence H. Kushi, Elad Ziv, Stephen K. Van Den Eeden, Eric Jorgenson, Thomas J. Hoffmann, Laurel A. Habel, John S. Witte, Lori C. Sakoda
Publié 2021

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

par Linda Kachuri, Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Paolo Vineis, Geoffrey Liu, Ghislaine Scelo, David Zaridze, Sanjay S. Shete, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, John K. Field, Michael P. Davies, M. Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Loïc Le Marchand, Iona Cheng, Matthew B. Schabath, Eric J. Duell, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne Arnold, James D. McKay, Nima C. Emami, Matthew T. Warkentin, Yonathan Brhane, Ma’en Obeidat, Richard M. Martin, Caroline Relton, George Davey Smith, Philip C. Haycock, Christopher I. Amos, Paul Brennan, John S. Witte, Rayjean J. Hung
Publié 2020