Mutagenesis screen uncovers lifespan extension through integrated stress response inhibition without reduced mRNA translation

por Maxime J. Derisbourg, Laura E. Wester, Ruth Baddi, Martin S. Denzel
Publicado 2021

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis

por Sabine Ruegenberg, Moritz Horn, Christian Pichlo, Kira Allmeroth, Ulrich Baumann, Martin S. Denzel
Publicado 2020

Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1

por Sabine Ruegenberg, Felix A. M. C. Mayr, Ilian Atanassov, Ulrich Baumann, Martin S. Denzel
Publicado 2021

NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants

por Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel
Publicado 2021