The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.

por Caroline E Lilley, Mira S Chaurushiya, Chris Boutell, Roger D Everett, Matthew D Weitzman
Publicado 2011

A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence.

por Chris Boutell, Delphine Cuchet-Lourenço, Emilia Vanni, Anne Orr, Mandy Glass, Steven McFarlane, Roger D Everett
Publicado 2011

SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.

por Delphine Cuchet-Lourenço, Chris Boutell, Vera Lukashchuk, Kyle Grant, Amanda Sykes, Jill Murray, Anne Orr, Roger D Everett
Publicado 2011