Genetic deficiency of NOD2 confers resistance to invasive aspergillosis

par Mark S. Gresnigt, Cristina Cunha, Martin Jaeger, Samuel M. Gonçalves, R. K. Subbarao Malireddi, Anne Ammerdorffer, Rosalie Lubbers, Marije Oosting, Orhan Rasid, Grégory Jouvion, Catherine Fitting, Dirk J. de Jong, João F. Lacerda, António Campos, Willem J. G. Melchers, Katrien Lagrou, Johan Maertens, Thirumala-Devi Kanneganti, Agostinho Carvalho, Oumaima Ibrahim-Granet, Frank L. van de Veerdonk
Publié 2018

Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

par Samuel M. Gonçalves, Daniela Antunes, Luis Leite, Toine Mercier, Rob ter Horst, Joana Vieira, Eduardo Espada, Carlos Pinho Vaz, Rosa Branca, Fernando Campilho, Fátima Freitas, Dário Ligeiro, António Marques, Frank L. van de Veerdonk, Leo A. B. Joosten, Katrien Lagrou, Johan Maertens, Mihai G. Netea, João F. Lacerda, António Campos, Cristina Cunha, Agostinho Carvalho
Publié 2021

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

par Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo Pereira, Miguel Fernández-García, Daniela Antunes, Cláudia S. Rodrigues, Catarina Barbosa-Matos, Joana Gaifem, Inês Mesquita, António Marques, Nuno S. Osório, Egídio Torrado, Fernando Rodrigues, Sandra Costa, Leo AB. Joosten, Katrien Lagrou, Johan Maertens, João F. Lacerda, António Campos, Gordon D. Brown, Axel A. Brakhage, Coral Barbas, Ricardo Silvestre, Frank L. van de Veerdonk, Georgios Chamilos, Mihai G. Netea, Jean-Paul Latgé, Cristina Cunha, Agostinho Carvalho
Publié 2020