NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.

by Ahmad Jalili, Kirsten D Mertz, Julia Romanov, Christine Wagner, Frank Kalthoff, Anton Stuetz, Gaurav Pathria, Melanie Gschaider, Georg Stingl, Stephan N Wagner
Published 2013

An attempt at a molecular prediction of metastasis in patients with primary cutaneous melanoma.

by Melanie Gschaider, Friederike Neumann, Bettina Peters, Florian Lenz, Michael Cibena, Malgorzata Goiser, Ingrid Wolf, Jörg Wenzel, Cornelia Mauch, Wolfgang Schreiner, Stephan N Wagner
Published 2012

B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma

by Johannes Griss, Wolfgang Bauer, Christine Wagner, Martin Simon, Minyi Chen, Katharina Grabmeier-Pfistershammer, Margarita Maurer-Granofszky, Florian Roka, Thomas Penz, Christoph Bock, Gao Zhang, Meenhard Herlyn, Katharina Glatz, Heinz Läubli, Kirsten D. Mertz, Peter Petzelbauer, Thomas Wiesner, Markus Hartl, Winfried F. Pickl, Rajasekharan Somasundaram, Peter Steinberger, Stephan N. Wagner
Published 2019

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

by Rajasekharan Somasundaram, Gao Zhang, Mizuho Fukunaga-Kalabis, Michela Perego, Clemens Krepler, Xiaowei Xu, Christine Wagner, Denitsa Hristova, Jie Zhang, Tian Tian, Zhi Wei, Qin Liu, Kanika Garg, Johannes Griss, Rufus Hards, Margarita Maurer, Christine Hafner, Marius Mayerhöfer, Georgios Karanikas, Ahmad Jalili, Verena Bauer-Pohl, Felix Weihsengruber, Klemens Rappersberger, Josef Koller, Roland Lang, Courtney Hudgens, Guo Chen, Michael Tetzlaff, Lawrence Wu, Dennie Tompers Frederick, Richard A. Scolyer, Georgina V. Long, Manashree Damle, Courtney Ellingsworth, Leon Grinman, Harry Choi, Brian J. Gavin, Margaret Dunagin, Arjun Raj, Nathalie Scholler, Laura Gross, Marilda Beqiri, Keiryn Bennett, Ian Watson, Helmut Schaider, Michael A. Davies, Jennifer Wargo, Brian J. Czerniecki, Lynn Schuchter, Dorothee Herlyn, Keith Flaherty, Meenhard Herlyn, Stephan N. Wagner
Published 2017