The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved.

por Izumi Miyabe, Thomas A Kunkel, Antony M Carr
Publicado 2011

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication

por Zhi-Xiong Zhou, Scott A. Lujan, Adam B. Burkholder, Marta A. Garbacz, Thomas A. Kunkel
Publicado 2019

High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication

por Jessica S. Williams, Percy P. Tumbale, Mercedes E. Arana, Julian A. Rana, R. Scott Williams, Thomas A. Kunkel
Publicado 2021

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break

por Andrea M. Kaminski, John M. Pryor, Dale A. Ramsden, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek
Publicado 2020

Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability.

por María-Victoria García-Ortíz, Stéphanie Marsin, Mercedes E Arana, Didier Gasparutto, Raphaël Guérois, Thomas A Kunkel, J Pablo Radicella
Publicado 2011

Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.

por Anna Aksenova, Kirill Volkov, Jaroslaw Maceluch, Zachary F Pursell, Igor B Rogozin, Thomas A Kunkel, Youri I Pavlov, Erik Johansson
Publicado 2010

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae

por Marta A. Garbacz, Scott A. Lujan, Adam B. Burkholder, Phillip B. Cox, Qiuqin Wu, Zhi-Xiong Zhou, James E. Haber, Thomas A. Kunkel
Publicado 2018

Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis

por Andrea M. Kaminski, Percy P. Tumbale, Matthew J. Schellenberg, R. Scott Williams, Jason G. Williams, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek
Publicado 2018

Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

por Joonas A. Jamsen, William A. Beard, Lars C. Pedersen, David D. Shock, Andrea F. Moon, Juno M. Krahn, Katarzyna Bebenek, Thomas A. Kunkel, Samuel H. Wilson
Publicado 2017