Pre-clinical modeling of cutaneous melanoma

Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with overcoming therapeutic plateau.

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Detalles Bibliográficos
Autores principales: Vito W. Rebecca, Rajasekharan Somasundaram, Meenhard Herlyn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/0003348e52b44f61bda3eaf9e47fe9f7
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Descripción
Sumario:Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with overcoming therapeutic plateau.