Pre-clinical modeling of cutaneous melanoma

Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with overcoming therapeutic plateau.

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Autores principales:	Vito W. Rebecca, Rajasekharan Somasundaram, Meenhard Herlyn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0003348e52b44f61bda3eaf9e47fe9f7
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spelling	oai:doaj.org-article:0003348e52b44f61bda3eaf9e47fe9f72021-12-02T17:51:12ZPre-clinical modeling of cutaneous melanoma10.1038/s41467-020-15546-92041-1723https://doaj.org/article/0003348e52b44f61bda3eaf9e47fe9f72020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15546-9https://doaj.org/toc/2041-1723Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with overcoming therapeutic plateau.Vito W. RebeccaRajasekharan SomasundaramMeenhard HerlynNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vito W. Rebecca Rajasekharan Somasundaram Meenhard Herlyn Pre-clinical modeling of cutaneous melanoma
description	Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with overcoming therapeutic plateau.
format	article
author	Vito W. Rebecca Rajasekharan Somasundaram Meenhard Herlyn
author_facet	Vito W. Rebecca Rajasekharan Somasundaram Meenhard Herlyn
author_sort	Vito W. Rebecca
title	Pre-clinical modeling of cutaneous melanoma
title_short	Pre-clinical modeling of cutaneous melanoma
title_full	Pre-clinical modeling of cutaneous melanoma
title_fullStr	Pre-clinical modeling of cutaneous melanoma
title_full_unstemmed	Pre-clinical modeling of cutaneous melanoma
title_sort	pre-clinical modeling of cutaneous melanoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0003348e52b44f61bda3eaf9e47fe9f7
work_keys_str_mv	AT vitowrebecca preclinicalmodelingofcutaneousmelanoma AT rajasekharansomasundaram preclinicalmodelingofcutaneousmelanoma AT meenhardherlyn preclinicalmodelingofcutaneousmelanoma
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Pre-clinical modeling of cutaneous melanoma

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