Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum

Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting associated with unfavourable outcomes during pregnancy. Here, Fejzo et al. perform genome-wide scans for HG and pregnancy nausea and vomiting and identify genetic associations at two loci implicating the genes GDF15 and IGFBP7.

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Autores principales: Marlena S. Fejzo, Olga V. Sazonova, J. Fah Sathirapongsasuti, Ingileif B. Hallgrímsdóttir, Vladimir Vacic, Kimber W. MacGibbon, Frederic P. Schoenberg, Nicholas Mancuso, Dennis J. Slamon, Patrick M. Mullin, 23andMe Research Team
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0004683069334187bf5574803b03f3fa
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spelling oai:doaj.org-article:0004683069334187bf5574803b03f3fa2021-12-02T16:49:21ZPlacenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum10.1038/s41467-018-03258-02041-1723https://doaj.org/article/0004683069334187bf5574803b03f3fa2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03258-0https://doaj.org/toc/2041-1723Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting associated with unfavourable outcomes during pregnancy. Here, Fejzo et al. perform genome-wide scans for HG and pregnancy nausea and vomiting and identify genetic associations at two loci implicating the genes GDF15 and IGFBP7.Marlena S. FejzoOlga V. SazonovaJ. Fah SathirapongsasutiIngileif B. HallgrímsdóttirVladimir VacicKimber W. MacGibbonFrederic P. SchoenbergNicholas MancusoDennis J. SlamonPatrick M. Mullin23andMe Research TeamNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marlena S. Fejzo
Olga V. Sazonova
J. Fah Sathirapongsasuti
Ingileif B. Hallgrímsdóttir
Vladimir Vacic
Kimber W. MacGibbon
Frederic P. Schoenberg
Nicholas Mancuso
Dennis J. Slamon
Patrick M. Mullin
23andMe Research Team
Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
description Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting associated with unfavourable outcomes during pregnancy. Here, Fejzo et al. perform genome-wide scans for HG and pregnancy nausea and vomiting and identify genetic associations at two loci implicating the genes GDF15 and IGFBP7.
format article
author Marlena S. Fejzo
Olga V. Sazonova
J. Fah Sathirapongsasuti
Ingileif B. Hallgrímsdóttir
Vladimir Vacic
Kimber W. MacGibbon
Frederic P. Schoenberg
Nicholas Mancuso
Dennis J. Slamon
Patrick M. Mullin
23andMe Research Team
author_facet Marlena S. Fejzo
Olga V. Sazonova
J. Fah Sathirapongsasuti
Ingileif B. Hallgrímsdóttir
Vladimir Vacic
Kimber W. MacGibbon
Frederic P. Schoenberg
Nicholas Mancuso
Dennis J. Slamon
Patrick M. Mullin
23andMe Research Team
author_sort Marlena S. Fejzo
title Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
title_short Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
title_full Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
title_fullStr Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
title_full_unstemmed Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
title_sort placenta and appetite genes gdf15 and igfbp7 are associated with hyperemesis gravidarum
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0004683069334187bf5574803b03f3fa
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