The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet

Introduction: Satureja Khuzestanica (S. Khuzestanica) is one of the native plants of Iran that grows in areas such as Khuzestan and Lorestan. The current study was designed to evaluate the effects of S. Khuzestanica on lipid profile, especially on decreasing serum cholesterol, liver enzymes, and lip...

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Autores principales: Sina Vakili, Fatemeh Zal, Ghasem Ebrahimi, Mahboobe Akbari, Mohammad Amin Momeni-Moghaddam
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Lenguaje:FA
Publicado: Shiraz University of Medical Sciences 2021
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Acceso en línea:https://doaj.org/article/000fe030b5e948cc8eac7677d0dcd6b7
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spelling oai:doaj.org-article:000fe030b5e948cc8eac7677d0dcd6b72021-12-02T19:50:16ZThe Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet2322-433910.30476/smsj.2021.84031.1072https://doaj.org/article/000fe030b5e948cc8eac7677d0dcd6b72021-05-01T00:00:00Zhttps://smsj.sums.ac.ir/article_47650_eeb40e50387916bbf56e7c1be515fda5.pdfhttps://doaj.org/toc/2322-4339Introduction: Satureja Khuzestanica (S. Khuzestanica) is one of the native plants of Iran that grows in areas such as Khuzestan and Lorestan. The current study was designed to evaluate the effects of S. Khuzestanica on lipid profile, especially on decreasing serum cholesterol, liver enzymes, and lipid peroxidation in male hamsters with high fat diet. Methods: 26 male hamsters were randomly divided into control, high fat diet (HFD), and high fat diet treated with S. Khuzestanica (HFD+S) groups. After 10 days of beginning the study, the two latter groups were fed with high fat diet for 30 days. During the last 10 days, the HFD+S group was treated with 100mg/kg/day S. Khuzestanica through the gavage. Results: Data showed that administration of S. Khuzestanica for 10 days resulted in a significant reduction of total cholesterol, LDL cholesterol, liver enzymes, and malondialdehyde in the HFD+S group. Conclusion: These results support the potential effects of the use of Satureia Khuzestanica in the prevention and treatment of cardiovascular diseases.Sina VakiliFatemeh ZalGhasem EbrahimiMahboobe AkbariMohammad Amin Momeni-MoghaddamShiraz University of Medical Sciencesarticlesaturejacardiovascular diseasesliverhigh fat dietoxidative stressMedicineRMedicine (General)R5-920FAمجله علوم پزشکی صدرا, Vol 9, Iss 2, Pp 133-144 (2021)
institution DOAJ
collection DOAJ
language FA
topic satureja
cardiovascular diseases
liver
high fat diet
oxidative stress
Medicine
R
Medicine (General)
R5-920
spellingShingle satureja
cardiovascular diseases
liver
high fat diet
oxidative stress
Medicine
R
Medicine (General)
R5-920
Sina Vakili
Fatemeh Zal
Ghasem Ebrahimi
Mahboobe Akbari
Mohammad Amin Momeni-Moghaddam
The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
description Introduction: Satureja Khuzestanica (S. Khuzestanica) is one of the native plants of Iran that grows in areas such as Khuzestan and Lorestan. The current study was designed to evaluate the effects of S. Khuzestanica on lipid profile, especially on decreasing serum cholesterol, liver enzymes, and lipid peroxidation in male hamsters with high fat diet. Methods: 26 male hamsters were randomly divided into control, high fat diet (HFD), and high fat diet treated with S. Khuzestanica (HFD+S) groups. After 10 days of beginning the study, the two latter groups were fed with high fat diet for 30 days. During the last 10 days, the HFD+S group was treated with 100mg/kg/day S. Khuzestanica through the gavage. Results: Data showed that administration of S. Khuzestanica for 10 days resulted in a significant reduction of total cholesterol, LDL cholesterol, liver enzymes, and malondialdehyde in the HFD+S group. Conclusion: These results support the potential effects of the use of Satureia Khuzestanica in the prevention and treatment of cardiovascular diseases.
format article
author Sina Vakili
Fatemeh Zal
Ghasem Ebrahimi
Mahboobe Akbari
Mohammad Amin Momeni-Moghaddam
author_facet Sina Vakili
Fatemeh Zal
Ghasem Ebrahimi
Mahboobe Akbari
Mohammad Amin Momeni-Moghaddam
author_sort Sina Vakili
title The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
title_short The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
title_full The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
title_fullStr The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
title_full_unstemmed The Effects of Satureja Khuzestanica on Lipid Profile, Liver Enzymes, and Oxidative Stress Markers in Male Hamsters with High Fat Diet
title_sort effects of satureja khuzestanica on lipid profile, liver enzymes, and oxidative stress markers in male hamsters with high fat diet
publisher Shiraz University of Medical Sciences
publishDate 2021
url https://doaj.org/article/000fe030b5e948cc8eac7677d0dcd6b7
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