EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy.

EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy.

Placental lactogen (PL) induced serotonergic signaling is essential for gestational β-cell mass expansion. We have previously shown that intact Epidermal growth factor -receptor (EGFR) function is a crucial component of this pathway. We now explored more specifically the link between EGFR and pregna...

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Autores principales: Elina Hakonen, Jarkko Ustinov, Jaan Palgi, Päivi J Miettinen, Timo Otonkoski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/002075132668414f9f07773864b4e741
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