MECHANISMS OF CELL RESISTANCE TO CYTOMEGALOVIRUS ARE CONNECTED WITH CELL PROLIFERATION STATE AND TRANSCRIPTION ACTIVITY OF LEUKOCYTE AND IMMUNE INTERFERON GENES

MECHANISMS OF CELL RESISTANCE TO CYTOMEGALOVIRUS ARE CONNECTED WITH CELL PROLIFERATION STATE AND TRANSCRIPTION ACTIVITY OF LEUKOCYTE AND IMMUNE INTERFERON GENES

Abstract. Cytomegalovirus (CMV) infection in diploid human fibroblasts (HF) and levels of cell resistance to this virus were shown to be in direct correlation with high α-interferon (IFNα) gene activity and induction of IFNγ gene transcription. Regulation of IFNα mRNA transcription was revealed to b...

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Autores principales: T. M. Sokolova, N. E. Fedorova, M. G. Medjidova, S. M. Terekhov, L. V. Uryvaev, A. A. Kushch
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2014
Materias:
human fibroblasts
interferon
mrna transcription
cytomegalovirus infection
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/0020f1c6cb6c4ec3a7c1421d867175e0
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