Relationship between insulin resistance and plasma vitamin D in adults

Alaa Badawi,1 Suzan Sayegh,2 Eman Sadoun,3 Mohamed Al-Thani,2 Paul Arora,4 Pierre S Haddad51Office of Biotechnology, Genomics and Population Health, Public Health Agency of Canada, Toronto, ON, Canada; 2Department of Public Health, 3Clinical Research Division, Supreme Council of Health, Doha, Qatar...

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Autores principales:	Badawi A, Sayegh S, Sadoun E, Al-Thani M, Arora P, Haddad PS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/002ae5de8de344248a8b39bb510eab45
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spelling	oai:doaj.org-article:002ae5de8de344248a8b39bb510eab452021-12-02T08:13:11ZRelationship between insulin resistance and plasma vitamin D in adults1178-7007https://doaj.org/article/002ae5de8de344248a8b39bb510eab452014-07-01T00:00:00Zhttp://www.dovepress.com/relationship-between-insulin-resistance-and-plasma-vitamin-d-in-adults-a17498https://doaj.org/toc/1178-7007 Alaa Badawi,1 Suzan Sayegh,2 Eman Sadoun,3 Mohamed Al-Thani,2 Paul Arora,4 Pierre S Haddad51Office of Biotechnology, Genomics and Population Health, Public Health Agency of Canada, Toronto, ON, Canada; 2Department of Public Health, 3Clinical Research Division, Supreme Council of Health, Doha, Qatar; 4Dalla Lana School of Public Health, University of Toronto, ON, Canada; 5Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, QC, CanadaAbstract: A recent relationship between vitamin D deficiency and the risk of type 2 diabetes mellitus (T2DM) and insulin resistance has been established through several studies. Research suggests a correlation between serum vitamin D and glycemic status measures. The aim of this study was to investigate the relationship between the plasma vitamin D levels (25[OH]D) and the factors linked to insulin resistance in a representative sample of Canadians ranging in age from 16–79 years. Data were used from the Canadian Health Measures Survey where direct measures of health and wellness were reported from 1,928 subjects. These data were gathered from March 2007–February 2009 at 15 sites selected through a multistage sampling strategy. An inverse relationship between insulin resistance and plasma vitamin D level in both men and women was observed. This study provides additional evidence for the role of vitamin D in T2DM. If causally associated, the supplementation of vitamin D may help in preventing insulin resistance and subsequent T2DM.Keywords: HOMA-IR, plasma 25(OH)D, diabetesBadawi ASayegh SSadoun EAl-Thani MArora PHaddad PSDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 297-303 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Badawi A Sayegh S Sadoun E Al-Thani M Arora P Haddad PS Relationship between insulin resistance and plasma vitamin D in adults
description	Alaa Badawi,1 Suzan Sayegh,2 Eman Sadoun,3 Mohamed Al-Thani,2 Paul Arora,4 Pierre S Haddad51Office of Biotechnology, Genomics and Population Health, Public Health Agency of Canada, Toronto, ON, Canada; 2Department of Public Health, 3Clinical Research Division, Supreme Council of Health, Doha, Qatar; 4Dalla Lana School of Public Health, University of Toronto, ON, Canada; 5Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, QC, CanadaAbstract: A recent relationship between vitamin D deficiency and the risk of type 2 diabetes mellitus (T2DM) and insulin resistance has been established through several studies. Research suggests a correlation between serum vitamin D and glycemic status measures. The aim of this study was to investigate the relationship between the plasma vitamin D levels (25[OH]D) and the factors linked to insulin resistance in a representative sample of Canadians ranging in age from 16–79 years. Data were used from the Canadian Health Measures Survey where direct measures of health and wellness were reported from 1,928 subjects. These data were gathered from March 2007–February 2009 at 15 sites selected through a multistage sampling strategy. An inverse relationship between insulin resistance and plasma vitamin D level in both men and women was observed. This study provides additional evidence for the role of vitamin D in T2DM. If causally associated, the supplementation of vitamin D may help in preventing insulin resistance and subsequent T2DM.Keywords: HOMA-IR, plasma 25(OH)D, diabetes
format	article
author	Badawi A Sayegh S Sadoun E Al-Thani M Arora P Haddad PS
author_facet	Badawi A Sayegh S Sadoun E Al-Thani M Arora P Haddad PS
author_sort	Badawi A
title	Relationship between insulin resistance and plasma vitamin D in adults
title_short	Relationship between insulin resistance and plasma vitamin D in adults
title_full	Relationship between insulin resistance and plasma vitamin D in adults
title_fullStr	Relationship between insulin resistance and plasma vitamin D in adults
title_full_unstemmed	Relationship between insulin resistance and plasma vitamin D in adults
title_sort	relationship between insulin resistance and plasma vitamin d in adults
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/002ae5de8de344248a8b39bb510eab45
work_keys_str_mv	AT badawia relationshipbetweeninsulinresistanceandplasmavitamindinadults AT sayeghs relationshipbetweeninsulinresistanceandplasmavitamindinadults AT sadoune relationshipbetweeninsulinresistanceandplasmavitamindinadults AT althanim relationshipbetweeninsulinresistanceandplasmavitamindinadults AT arorap relationshipbetweeninsulinresistanceandplasmavitamindinadults AT haddadps relationshipbetweeninsulinresistanceandplasmavitamindinadults
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Relationship between insulin resistance and plasma vitamin D in adults

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