Electrogenic metals in epidermis: connection with cell bioenergetics

We have found out in our previous studies that results of quantitative spectrometry of electrogenic metals (Ca, K, Na) in epidermal cells (hair) of healthy people and the Chernobyl liquidators (chronic oxidative/nitrosative stress) are conjugated. The nature of this «conjugation», like many intimate...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: V. I. Petukhov, E. V. Dmitriev, L. K. Baumane, A. V. Skalny, Y. N. Lobanova
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/002eaa573d154a318f39b3a648664d84
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:We have found out in our previous studies that results of quantitative spectrometry of electrogenic metals (Ca, K, Na) in epidermal cells (hair) of healthy people and the Chernobyl liquidators (chronic oxidative/nitrosative stress) are conjugated. The nature of this «conjugation», like many intimate mechanisms of the metal-ligand homeostasis in the epidermis, remains unsolved. Transmembrane traffic of electrogenic metals (and especially the Na+ ion) is directly related to cell bioenergetics. Therefore, intracellular bioenergetics processes in the membrane and in the mitochondrial respiratory chain, can determine homeostasis of electrogenic metals. It has been shown that in the cell, that is an open dynamic system, there are signs of self-organized criticality (SC). Thus we can classify electrogenic metal homeostasis as SC-phenomenon.