An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins

Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichment, providing the basis for more comprehensive gl...

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Autores principales:	Haopeng Xiao, Weixuan Chen, Johanna M. Smeekens, Ronghu Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/003e950ab8cd4085b921ab58ee0f6809
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spelling	oai:doaj.org-article:003e950ab8cd4085b921ab58ee0f68092021-12-02T17:33:00ZAn enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins10.1038/s41467-018-04081-32041-1723https://doaj.org/article/003e950ab8cd4085b921ab58ee0f68092018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04081-3https://doaj.org/toc/2041-1723Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichment, providing the basis for more comprehensive glycoprotein analyses.Haopeng XiaoWeixuan ChenJohanna M. SmeekensRonghu WuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Haopeng Xiao Weixuan Chen Johanna M. Smeekens Ronghu Wu An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
description	Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichment, providing the basis for more comprehensive glycoprotein analyses.
format	article
author	Haopeng Xiao Weixuan Chen Johanna M. Smeekens Ronghu Wu
author_facet	Haopeng Xiao Weixuan Chen Johanna M. Smeekens Ronghu Wu
author_sort	Haopeng Xiao
title	An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
title_short	An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
title_full	An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
title_fullStr	An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
title_full_unstemmed	An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
title_sort	enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/003e950ab8cd4085b921ab58ee0f6809
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An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins

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