A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study

Abstract Background Breast cancer surgery frequently causes deficiencies in shoulder functioning. The study pourpode is to identify risk factors for prolonged pain, reduction in function, and decrease in range of motion (ROM) in BC patients. Methods A prospective cohort study was designed in a priva...

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Autores principales:	Ifat Klein, Leonid Kalichman, Noy Chen, Sergio Susmallian
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Functional limitations Pain Physical activity Physical therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/004ea8e37ad6492ba201a7f4c4b4a4c7
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spelling	oai:doaj.org-article:004ea8e37ad6492ba201a7f4c4b4a4c72021-11-21T12:30:24ZA comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study10.1186/s12885-021-08891-51471-2407https://doaj.org/article/004ea8e37ad6492ba201a7f4c4b4a4c72021-11-01T00:00:00Zhttps://doi.org/10.1186/s12885-021-08891-5https://doaj.org/toc/1471-2407Abstract Background Breast cancer surgery frequently causes deficiencies in shoulder functioning. The study pourpode is to identify risk factors for prolonged pain, reduction in function, and decrease in range of motion (ROM) in BC patients. Methods A prospective cohort study was designed in a private hospital; between October 2018 and April 2019 with a follow-up of 6 months. Patients following BC surgery, were divided by arm morbidities, and the different risk facrors were evaluated using univariate analysis and logistic regression. Results A total of 157 patients were included in the study. Risk factors for functional disabilities included; pain levels during hospitalization NPRS 1.2 (±0.8) compared to patients with no disabilities 0.5 ± 0.7 (p = .006), the size of tumors more than 1.4 ± 0.8 cm. compared with no morbidities 0.8 ± 0.9 cm. (p = .046), and breast reconstructions (p = .030). Risk factors for prolonged pain includes mastectomy (p = .006), breast reconstruction (p = .011), more than three dissected lymph nodes (p = .002), the presence of preoperative pain (p < .001), in-hospital pain (p < .001), axillary web syndrome (p < .001) and lymphedema (p < .001). Risk factors for decreased ROM were more than three dissected lymph nodes (p = .027), radiation (p = .018), and the size of dissected tissue (p = .035). Postoperative physical therapy appears to reduce the incidence of prolonged pain (p = .013) and regular physical activity may reduce long term functional disabilities (p = .021). Conclusions Upper arm morbidity following BC treatments affect up to 70% of the patients. Identifying the different risk and beneficial factors may improve awareness among physicians to refer patients to early rehabilitation programs and thus avoid chronic morbidity and improve the course of recovery. Trial registration The study was registered in Clinical trial with the ID number: NCT03389204 .Ifat KleinLeonid KalichmanNoy ChenSergio SusmallianBMCarticleFunctional limitationsPainPhysical activityPhysical therapyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Functional limitations Pain Physical activity Physical therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Functional limitations Pain Physical activity Physical therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Ifat Klein Leonid Kalichman Noy Chen Sergio Susmallian A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
description	Abstract Background Breast cancer surgery frequently causes deficiencies in shoulder functioning. The study pourpode is to identify risk factors for prolonged pain, reduction in function, and decrease in range of motion (ROM) in BC patients. Methods A prospective cohort study was designed in a private hospital; between October 2018 and April 2019 with a follow-up of 6 months. Patients following BC surgery, were divided by arm morbidities, and the different risk facrors were evaluated using univariate analysis and logistic regression. Results A total of 157 patients were included in the study. Risk factors for functional disabilities included; pain levels during hospitalization NPRS 1.2 (±0.8) compared to patients with no disabilities 0.5 ± 0.7 (p = .006), the size of tumors more than 1.4 ± 0.8 cm. compared with no morbidities 0.8 ± 0.9 cm. (p = .046), and breast reconstructions (p = .030). Risk factors for prolonged pain includes mastectomy (p = .006), breast reconstruction (p = .011), more than three dissected lymph nodes (p = .002), the presence of preoperative pain (p < .001), in-hospital pain (p < .001), axillary web syndrome (p < .001) and lymphedema (p < .001). Risk factors for decreased ROM were more than three dissected lymph nodes (p = .027), radiation (p = .018), and the size of dissected tissue (p = .035). Postoperative physical therapy appears to reduce the incidence of prolonged pain (p = .013) and regular physical activity may reduce long term functional disabilities (p = .021). Conclusions Upper arm morbidity following BC treatments affect up to 70% of the patients. Identifying the different risk and beneficial factors may improve awareness among physicians to refer patients to early rehabilitation programs and thus avoid chronic morbidity and improve the course of recovery. Trial registration The study was registered in Clinical trial with the ID number: NCT03389204 .
format	article
author	Ifat Klein Leonid Kalichman Noy Chen Sergio Susmallian
author_facet	Ifat Klein Leonid Kalichman Noy Chen Sergio Susmallian
author_sort	Ifat Klein
title	A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
title_short	A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
title_full	A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
title_fullStr	A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
title_full_unstemmed	A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
title_sort	comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study
publisher	BMC
publishDate	2021
url	https://doaj.org/article/004ea8e37ad6492ba201a7f4c4b4a4c7
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A comprehensive approach to risk factors for upper arm morbidities following breast cancer treatment: a prospective study

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