Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo

Bacterial phytochrome-based probes improved sensitivity in photoacoustic computed tomography. Here the authors engineer a small near-infrared switchable photochromic probe that allows multi-contrast imaging at depths and can be adapted to study protein–protein interactions in deep-seated tumors.

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Autores principales: Lei Li, Anton A. Shemetov, Mikhail Baloban, Peng Hu, Liren Zhu, Daria M. Shcherbakova, Ruiying Zhang, Junhui Shi, Junjie Yao, Lihong V. Wang, Vladislav V. Verkhusha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0053d01fad004692b2ccf75bf24c2a9e
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spelling oai:doaj.org-article:0053d01fad004692b2ccf75bf24c2a9e2021-12-02T16:56:59ZSmall near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo10.1038/s41467-018-05231-32041-1723https://doaj.org/article/0053d01fad004692b2ccf75bf24c2a9e2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05231-3https://doaj.org/toc/2041-1723Bacterial phytochrome-based probes improved sensitivity in photoacoustic computed tomography. Here the authors engineer a small near-infrared switchable photochromic probe that allows multi-contrast imaging at depths and can be adapted to study protein–protein interactions in deep-seated tumors.Lei LiAnton A. ShemetovMikhail BalobanPeng HuLiren ZhuDaria M. ShcherbakovaRuiying ZhangJunhui ShiJunjie YaoLihong V. WangVladislav V. VerkhushaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lei Li
Anton A. Shemetov
Mikhail Baloban
Peng Hu
Liren Zhu
Daria M. Shcherbakova
Ruiying Zhang
Junhui Shi
Junjie Yao
Lihong V. Wang
Vladislav V. Verkhusha
Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
description Bacterial phytochrome-based probes improved sensitivity in photoacoustic computed tomography. Here the authors engineer a small near-infrared switchable photochromic probe that allows multi-contrast imaging at depths and can be adapted to study protein–protein interactions in deep-seated tumors.
format article
author Lei Li
Anton A. Shemetov
Mikhail Baloban
Peng Hu
Liren Zhu
Daria M. Shcherbakova
Ruiying Zhang
Junhui Shi
Junjie Yao
Lihong V. Wang
Vladislav V. Verkhusha
author_facet Lei Li
Anton A. Shemetov
Mikhail Baloban
Peng Hu
Liren Zhu
Daria M. Shcherbakova
Ruiying Zhang
Junhui Shi
Junjie Yao
Lihong V. Wang
Vladislav V. Verkhusha
author_sort Lei Li
title Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
title_short Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
title_full Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
title_fullStr Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
title_full_unstemmed Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
title_sort small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0053d01fad004692b2ccf75bf24c2a9e
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