Oropharyngeal mucosal transmission of Zika virus in rhesus macaques

Oropharyngeal mucosal transmission of Zika virus in rhesus macaques

Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that transmission risk from saliva of infected animals...

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Autores principales: Christina M. Newman, Dawn M. Dudley, Matthew T. Aliota, Andrea M. Weiler, Gabrielle L. Barry, Mariel S. Mohns, Meghan E. Breitbach, Laurel M. Stewart, Connor R. Buechler, Michael E. Graham, Jennifer Post, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano, David H. O’Connor, Thomas C. Friedrich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
Q
Acceso en línea:https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d85
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Sumario:Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that transmission risk from saliva of infected animals is low.

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