Oropharyngeal mucosal transmission of Zika virus in rhesus macaques

Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that transmission risk from saliva of infected animals...

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Autores principales:	Christina M. Newman, Dawn M. Dudley, Matthew T. Aliota, Andrea M. Weiler, Gabrielle L. Barry, Mariel S. Mohns, Meghan E. Breitbach, Laurel M. Stewart, Connor R. Buechler, Michael E. Graham, Jennifer Post, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano, David H. O’Connor, Thomas C. Friedrich
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d85
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spelling	oai:doaj.org-article:00564ee8a1ce45af98f5098b776f6d852021-12-02T14:16:14ZOropharyngeal mucosal transmission of Zika virus in rhesus macaques10.1038/s41467-017-00246-82041-1723https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d852017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00246-8https://doaj.org/toc/2041-1723Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that transmission risk from saliva of infected animals is low.Christina M. NewmanDawn M. DudleyMatthew T. AliotaAndrea M. WeilerGabrielle L. BarryMariel S. MohnsMeghan E. BreitbachLaurel M. StewartConnor R. BuechlerMichael E. GrahamJennifer PostNancy Schultz-DarkenEric PetersonWendy NewtonEmma L. MohrSaverio CapuanoDavid H. O’ConnorThomas C. FriedrichNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christina M. Newman Dawn M. Dudley Matthew T. Aliota Andrea M. Weiler Gabrielle L. Barry Mariel S. Mohns Meghan E. Breitbach Laurel M. Stewart Connor R. Buechler Michael E. Graham Jennifer Post Nancy Schultz-Darken Eric Peterson Wendy Newton Emma L. Mohr Saverio Capuano David H. O’Connor Thomas C. Friedrich Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
description	Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that transmission risk from saliva of infected animals is low.
format	article
author	Christina M. Newman Dawn M. Dudley Matthew T. Aliota Andrea M. Weiler Gabrielle L. Barry Mariel S. Mohns Meghan E. Breitbach Laurel M. Stewart Connor R. Buechler Michael E. Graham Jennifer Post Nancy Schultz-Darken Eric Peterson Wendy Newton Emma L. Mohr Saverio Capuano David H. O’Connor Thomas C. Friedrich
author_facet	Christina M. Newman Dawn M. Dudley Matthew T. Aliota Andrea M. Weiler Gabrielle L. Barry Mariel S. Mohns Meghan E. Breitbach Laurel M. Stewart Connor R. Buechler Michael E. Graham Jennifer Post Nancy Schultz-Darken Eric Peterson Wendy Newton Emma L. Mohr Saverio Capuano David H. O’Connor Thomas C. Friedrich
author_sort	Christina M. Newman
title	Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
title_short	Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
title_full	Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
title_fullStr	Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
title_full_unstemmed	Oropharyngeal mucosal transmission of Zika virus in rhesus macaques
title_sort	oropharyngeal mucosal transmission of zika virus in rhesus macaques
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d85
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Oropharyngeal mucosal transmission of Zika virus in rhesus macaques

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