The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.
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Nature Portfolio
2021
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oai:doaj.org-article:005c24fb0ae4423db9855a4fda43b7ac2021-12-02T17:12:16ZThe Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation10.1038/s41467-021-24131-72041-1723https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24131-7https://doaj.org/toc/2041-1723The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.Feng LiTsz Y. LoLeann MilesQin WangHarun N. NoristaniDan LiJingwen NiuShannon TrombleyJessica I. GoldshteynChuxi WangShuchao WangJingyun QiuKatarzyna PogodaKalpana MandalMegan BrewsterPanteleimon RompolasYe HePaul A. JanmeyGareth M. ThomasShuxin LiYuanquan SongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Feng Li Tsz Y. Lo Leann Miles Qin Wang Harun N. Noristani Dan Li Jingwen Niu Shannon Trombley Jessica I. Goldshteyn Chuxi Wang Shuchao Wang Jingyun Qiu Katarzyna Pogoda Kalpana Mandal Megan Brewster Panteleimon Rompolas Ye He Paul A. Janmey Gareth M. Thomas Shuxin Li Yuanquan Song The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| description |
The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery. |
| format |
article |
| author |
Feng Li Tsz Y. Lo Leann Miles Qin Wang Harun N. Noristani Dan Li Jingwen Niu Shannon Trombley Jessica I. Goldshteyn Chuxi Wang Shuchao Wang Jingyun Qiu Katarzyna Pogoda Kalpana Mandal Megan Brewster Panteleimon Rompolas Ye He Paul A. Janmey Gareth M. Thomas Shuxin Li Yuanquan Song |
| author_facet |
Feng Li Tsz Y. Lo Leann Miles Qin Wang Harun N. Noristani Dan Li Jingwen Niu Shannon Trombley Jessica I. Goldshteyn Chuxi Wang Shuchao Wang Jingyun Qiu Katarzyna Pogoda Kalpana Mandal Megan Brewster Panteleimon Rompolas Ye He Paul A. Janmey Gareth M. Thomas Shuxin Li Yuanquan Song |
| author_sort |
Feng Li |
| title |
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| title_short |
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| title_full |
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| title_fullStr |
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| title_full_unstemmed |
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation |
| title_sort |
atr-chek1 pathway inhibits axon regeneration in response to piezo-dependent mechanosensation |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac |
| work_keys_str_mv |
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1718381417582297088 |