The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.

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Autores principales: Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac
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