A biomimetic chiral-driven ionic gate constructed by pillar[6]arene-based host–guest systems

Uptake and release of glucose is regulated by glucose-sensitive ion channels, but complexity of the system impedes investigation of the gating behavior under physiological conditions. Here the authors use a pillararene based artificial ion channel to mimic and investigate chirality driven switching...

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Auteurs principaux: Yue Sun, Fan Zhang, Jiaxin Quan, Fei Zhu, Wei Hong, Junkai Ma, Huan Pang, Yao Sun, Demei Tian, Haibing Li
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/005ce02a287d4951b3543a2ded6fdfa0
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Résumé:Uptake and release of glucose is regulated by glucose-sensitive ion channels, but complexity of the system impedes investigation of the gating behavior under physiological conditions. Here the authors use a pillararene based artificial ion channel to mimic and investigate chirality driven switching of a glucose ion channel.