A self-destructive nanosweeper that captures and clears amyloid β-peptides

Cerebral amyloid β-peptide accumulation is a causative factor in Alzheimer’s Disease. Here the authors design a 'nanosweeper' that binds amyloid β-peptide and induces autophagy to clear the accumulated plagues.

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Autores principales: Qiang Luo, Yao-Xin Lin, Pei-Pei Yang, Yi Wang, Guo-Bin Qi, Zeng-Ying Qiao, Bing-Nan Li, Kuo Zhang, Jing-Ping Zhang, Lei Wang, Hao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0060f6cc05824127a3a8daa3cfc9ad8b
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spelling oai:doaj.org-article:0060f6cc05824127a3a8daa3cfc9ad8b2021-12-02T16:49:51ZA self-destructive nanosweeper that captures and clears amyloid β-peptides10.1038/s41467-018-04255-z2041-1723https://doaj.org/article/0060f6cc05824127a3a8daa3cfc9ad8b2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04255-zhttps://doaj.org/toc/2041-1723Cerebral amyloid β-peptide accumulation is a causative factor in Alzheimer’s Disease. Here the authors design a 'nanosweeper' that binds amyloid β-peptide and induces autophagy to clear the accumulated plagues.Qiang LuoYao-Xin LinPei-Pei YangYi WangGuo-Bin QiZeng-Ying QiaoBing-Nan LiKuo ZhangJing-Ping ZhangLei WangHao WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qiang Luo
Yao-Xin Lin
Pei-Pei Yang
Yi Wang
Guo-Bin Qi
Zeng-Ying Qiao
Bing-Nan Li
Kuo Zhang
Jing-Ping Zhang
Lei Wang
Hao Wang
A self-destructive nanosweeper that captures and clears amyloid β-peptides
description Cerebral amyloid β-peptide accumulation is a causative factor in Alzheimer’s Disease. Here the authors design a 'nanosweeper' that binds amyloid β-peptide and induces autophagy to clear the accumulated plagues.
format article
author Qiang Luo
Yao-Xin Lin
Pei-Pei Yang
Yi Wang
Guo-Bin Qi
Zeng-Ying Qiao
Bing-Nan Li
Kuo Zhang
Jing-Ping Zhang
Lei Wang
Hao Wang
author_facet Qiang Luo
Yao-Xin Lin
Pei-Pei Yang
Yi Wang
Guo-Bin Qi
Zeng-Ying Qiao
Bing-Nan Li
Kuo Zhang
Jing-Ping Zhang
Lei Wang
Hao Wang
author_sort Qiang Luo
title A self-destructive nanosweeper that captures and clears amyloid β-peptides
title_short A self-destructive nanosweeper that captures and clears amyloid β-peptides
title_full A self-destructive nanosweeper that captures and clears amyloid β-peptides
title_fullStr A self-destructive nanosweeper that captures and clears amyloid β-peptides
title_full_unstemmed A self-destructive nanosweeper that captures and clears amyloid β-peptides
title_sort self-destructive nanosweeper that captures and clears amyloid β-peptides
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0060f6cc05824127a3a8daa3cfc9ad8b
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