Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia

BACKGROUND AND OBJECTIVE: Acute post ERCP pancreatitis (PEP) is still the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), and the reported incidence ranges between 5% and 20%. This difference reflects variety of patient populations, indications, definition of pancr...

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Autores principales:	J Shokry Shirvany, MT Hamidian, N Meftah, N Nikbakhsh, R Modarres, H Taheri, M Kashifard, SH Savadkouhi, AA Darzi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2011
Materias:	endoscopic retrograde cholangiopancreatography acute pancreatitis hyperamylasemia Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/006e786906144d839b5878678eb9243c
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spelling	oai:doaj.org-article:006e786906144d839b5878678eb9243c2021-11-10T08:56:58ZRisk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia1561-41072251-7170https://doaj.org/article/006e786906144d839b5878678eb9243c2011-11-01T00:00:00Zhttp://jbums.org/article-1-3927-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Acute post ERCP pancreatitis (PEP) is still the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), and the reported incidence ranges between 5% and 20%. This difference reflects variety of patient populations, indications, definition of pancreatitis, endoscopic expertise and data collection methods. This study was designed to examine the incidents of post ERCP pancreatitis and hyperamylasemia and related risk factors from a tertiary academic medical center of North of IranMETHODS: This retrospective study was performed on all patients who underwent ERCP in Shahid Beheshti hospital (Babol Iran) during 2005-2009. Patients presented with acute pancreatitis and history of endoscopic sphincterotomy were excluded. Age, gender, CBD diameter, type of sphincterotomy, opium consumption and liver enzyme were the main variable for final analysis.FINDINGS: The overall incidence of PEP was 8.2% (43 of 525 patients) and post ERCP hypramilasemia developed in 34% of patients. In multivariate analysis, independent risk factors for PEP were: age less than 40 (OR=3/2, p<0.001) and needle knife Sphincterotomy (NKS) (OR=2/2 p<0.015). The independent risk factor of PERCP hyperamylasemia were age less than 40 (OR=1.8, p<0.04) and intact gallbladder without stone (OR=1.6, p<0.01). CONCLUSION: The results of this study show that young age is independently associated with post ERCP pancreatitis and hyperamylasemia. NKS increase PEP and intact gallbellader is predictor of post ERCP hyperamylasemia.J Shokry Shirvany,MT HamidianN Meftah,N NikbakhshR ModarresH Taheri,M KashifardSH SavadkouhiAA DarziBabol University of Medical Sciencesarticleendoscopic retrograde cholangiopancreatographyacute pancreatitishyperamylasemiaMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 6, Pp 67-72 (2011)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	endoscopic retrograde cholangiopancreatography acute pancreatitis hyperamylasemia Medicine R Medicine (General) R5-920
spellingShingle	endoscopic retrograde cholangiopancreatography acute pancreatitis hyperamylasemia Medicine R Medicine (General) R5-920 J Shokry Shirvany, MT Hamidian N Meftah, N Nikbakhsh R Modarres H Taheri, M Kashifard SH Savadkouhi AA Darzi Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
description	BACKGROUND AND OBJECTIVE: Acute post ERCP pancreatitis (PEP) is still the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), and the reported incidence ranges between 5% and 20%. This difference reflects variety of patient populations, indications, definition of pancreatitis, endoscopic expertise and data collection methods. This study was designed to examine the incidents of post ERCP pancreatitis and hyperamylasemia and related risk factors from a tertiary academic medical center of North of IranMETHODS: This retrospective study was performed on all patients who underwent ERCP in Shahid Beheshti hospital (Babol Iran) during 2005-2009. Patients presented with acute pancreatitis and history of endoscopic sphincterotomy were excluded. Age, gender, CBD diameter, type of sphincterotomy, opium consumption and liver enzyme were the main variable for final analysis.FINDINGS: The overall incidence of PEP was 8.2% (43 of 525 patients) and post ERCP hypramilasemia developed in 34% of patients. In multivariate analysis, independent risk factors for PEP were: age less than 40 (OR=3/2, p<0.001) and needle knife Sphincterotomy (NKS) (OR=2/2 p<0.015). The independent risk factor of PERCP hyperamylasemia were age less than 40 (OR=1.8, p<0.04) and intact gallbladder without stone (OR=1.6, p<0.01). CONCLUSION: The results of this study show that young age is independently associated with post ERCP pancreatitis and hyperamylasemia. NKS increase PEP and intact gallbellader is predictor of post ERCP hyperamylasemia.
format	article
author	J Shokry Shirvany, MT Hamidian N Meftah, N Nikbakhsh R Modarres H Taheri, M Kashifard SH Savadkouhi AA Darzi
author_facet	J Shokry Shirvany, MT Hamidian N Meftah, N Nikbakhsh R Modarres H Taheri, M Kashifard SH Savadkouhi AA Darzi
author_sort	J Shokry Shirvany,
title	Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
title_short	Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
title_full	Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
title_fullStr	Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
title_full_unstemmed	Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia
title_sort	risk factors for post endoscopic retrograde cholangiopancreatography pancreatitis and hyperamylasemia
publisher	Babol University of Medical Sciences
publishDate	2011
url	https://doaj.org/article/006e786906144d839b5878678eb9243c
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Risk Factors for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia

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