The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study
Objective: The aim of this study was to explore the association between exposure to particulate matter with an aerodynamic diameter of 2.5 mm or less (PM2.5) and blood pressure (BP) levels in children and adolescents and to illustrate the impact of PM2.5 levels on BP growth curves in a cohort study....
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Elsevier
2022
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oai:doaj.org-article:006eb7c5226d403896bb8c50a4d3c1552021-12-04T04:32:07ZThe impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study0160-412010.1016/j.envint.2021.107012https://doaj.org/article/006eb7c5226d403896bb8c50a4d3c1552022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0160412021006371https://doaj.org/toc/0160-4120Objective: The aim of this study was to explore the association between exposure to particulate matter with an aerodynamic diameter of 2.5 mm or less (PM2.5) and blood pressure (BP) levels in children and adolescents and to illustrate the impact of PM2.5 levels on BP growth curves in a cohort study. Methods: A longitudinal study was designed and included 4303 children (7617 BP measurements) living in the selected areas, and evaluations were conducted in 2014–2015 (visit 1) and followed up in 2019 (visit 2). Two-stage stratified cluster sampling was used to include urban–rural areas. A mixed linear regression model and mixed logistic regression model were used to analyze the effect of PM2.5 exposure on BP and the incidence of prehypertension and hypertension in children. Results: After adjusting for covariates, systolic blood pressure (SBP) (2.21 (95% CIs: 0. 81, 3.62), mmHg), diastolic blood pressure (DBP) (1.92 (95% CIs: 0.74, 3.11), mmHg), mean arterial pressure (MAP) (2.03 (95% CIs: 0.89, 3.17), mmHg) and heart rate (HR) (2.24 (95% CIs: 0.11, 4.37), beats/min) increased significantly in the fourth quartile of PM2.5 exposure levels compared with the first quartile (all P < 0.01). In addition, long-term exposure to PM2.5 was significantly positively correlated with SBP, DBP and MAP, and the effect was more notable in urban areas than that in rural areas. Moreover, the risk of prehypertension and hypertension incidence increased by 1.17 (95% CIs: 1.03, 1.33) fold with a one-quartile increase in PM2.5 exposure. The long-term effects of annual mean PM2.5 exposure on SBP, DBP and MAP were significant from pregnancy to 7, 3 and 4 years of age, respectively. Conclusion: Long-term exposure to PM2.5 was positively associated with growth curves of hemodynamics indexed from pregnancy to childhood and adolescence, and the effect was more significant in urban areas than in rural areas.Xiaohua LiangJingyu ChenXizhou AnFangchao LiuFengchao LiangXian TangPing QuElsevierarticleAir pollutionBlood pressureGrowth curveChildren and adolescentsUrban-rural areasEnvironmental sciencesGE1-350ENEnvironment International, Vol 158, Iss , Pp 107012- (2022) |
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DOAJ |
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EN |
| topic |
Air pollution Blood pressure Growth curve Children and adolescents Urban-rural areas Environmental sciences GE1-350 |
| spellingShingle |
Air pollution Blood pressure Growth curve Children and adolescents Urban-rural areas Environmental sciences GE1-350 Xiaohua Liang Jingyu Chen Xizhou An Fangchao Liu Fengchao Liang Xian Tang Ping Qu The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| description |
Objective: The aim of this study was to explore the association between exposure to particulate matter with an aerodynamic diameter of 2.5 mm or less (PM2.5) and blood pressure (BP) levels in children and adolescents and to illustrate the impact of PM2.5 levels on BP growth curves in a cohort study. Methods: A longitudinal study was designed and included 4303 children (7617 BP measurements) living in the selected areas, and evaluations were conducted in 2014–2015 (visit 1) and followed up in 2019 (visit 2). Two-stage stratified cluster sampling was used to include urban–rural areas. A mixed linear regression model and mixed logistic regression model were used to analyze the effect of PM2.5 exposure on BP and the incidence of prehypertension and hypertension in children. Results: After adjusting for covariates, systolic blood pressure (SBP) (2.21 (95% CIs: 0. 81, 3.62), mmHg), diastolic blood pressure (DBP) (1.92 (95% CIs: 0.74, 3.11), mmHg), mean arterial pressure (MAP) (2.03 (95% CIs: 0.89, 3.17), mmHg) and heart rate (HR) (2.24 (95% CIs: 0.11, 4.37), beats/min) increased significantly in the fourth quartile of PM2.5 exposure levels compared with the first quartile (all P < 0.01). In addition, long-term exposure to PM2.5 was significantly positively correlated with SBP, DBP and MAP, and the effect was more notable in urban areas than that in rural areas. Moreover, the risk of prehypertension and hypertension incidence increased by 1.17 (95% CIs: 1.03, 1.33) fold with a one-quartile increase in PM2.5 exposure. The long-term effects of annual mean PM2.5 exposure on SBP, DBP and MAP were significant from pregnancy to 7, 3 and 4 years of age, respectively. Conclusion: Long-term exposure to PM2.5 was positively associated with growth curves of hemodynamics indexed from pregnancy to childhood and adolescence, and the effect was more significant in urban areas than in rural areas. |
| format |
article |
| author |
Xiaohua Liang Jingyu Chen Xizhou An Fangchao Liu Fengchao Liang Xian Tang Ping Qu |
| author_facet |
Xiaohua Liang Jingyu Chen Xizhou An Fangchao Liu Fengchao Liang Xian Tang Ping Qu |
| author_sort |
Xiaohua Liang |
| title |
The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| title_short |
The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| title_full |
The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| title_fullStr |
The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| title_full_unstemmed |
The impact of PM2.5 on children’s blood pressure growth curves: A prospective cohort study |
| title_sort |
impact of pm2.5 on children’s blood pressure growth curves: a prospective cohort study |
| publisher |
Elsevier |
| publishDate |
2022 |
| url |
https://doaj.org/article/006eb7c5226d403896bb8c50a4d3c155 |
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