ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability

MDC1 is a key component of the DNA damage response and interacts with several factors such as γ-H2AX. Here the authors show that MDC1 interacts with ID3, facilitating MDC1 recruitment to sites of damage and repair of breaks.

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Autores principales:	Jung-Hee Lee, Seon-Joo Park, Gurusamy Hariharasudhan, Min-Ji Kim, Sung Mi Jung, Seo-Yeon Jeong, In-Youb Chang, Cheolhee Kim, Eunae Kim, Jihyeon Yu, Sangsu Bae, Ho Jin You
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/007860f605384277afd41715279532d2
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spelling	oai:doaj.org-article:007860f605384277afd41715279532d22021-12-02T15:37:06ZID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability10.1038/s41467-017-01051-z2041-1723https://doaj.org/article/007860f605384277afd41715279532d22017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01051-zhttps://doaj.org/toc/2041-1723MDC1 is a key component of the DNA damage response and interacts with several factors such as γ-H2AX. Here the authors show that MDC1 interacts with ID3, facilitating MDC1 recruitment to sites of damage and repair of breaks.Jung-Hee LeeSeon-Joo ParkGurusamy HariharasudhanMin-Ji KimSung Mi JungSeo-Yeon JeongIn-Youb ChangCheolhee KimEunae KimJihyeon YuSangsu BaeHo Jin YouNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jung-Hee Lee Seon-Joo Park Gurusamy Hariharasudhan Min-Ji Kim Sung Mi Jung Seo-Yeon Jeong In-Youb Chang Cheolhee Kim Eunae Kim Jihyeon Yu Sangsu Bae Ho Jin You ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
description	MDC1 is a key component of the DNA damage response and interacts with several factors such as γ-H2AX. Here the authors show that MDC1 interacts with ID3, facilitating MDC1 recruitment to sites of damage and repair of breaks.
format	article
author	Jung-Hee Lee Seon-Joo Park Gurusamy Hariharasudhan Min-Ji Kim Sung Mi Jung Seo-Yeon Jeong In-Youb Chang Cheolhee Kim Eunae Kim Jihyeon Yu Sangsu Bae Ho Jin You
author_facet	Jung-Hee Lee Seon-Joo Park Gurusamy Hariharasudhan Min-Ji Kim Sung Mi Jung Seo-Yeon Jeong In-Youb Chang Cheolhee Kim Eunae Kim Jihyeon Yu Sangsu Bae Ho Jin You
author_sort	Jung-Hee Lee
title	ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
title_short	ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
title_full	ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
title_fullStr	ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
title_full_unstemmed	ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
title_sort	id3 regulates the mdc1-mediated dna damage response in order to maintain genome stability
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/007860f605384277afd41715279532d2
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ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability

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