Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca<sup>2+</sup>-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
ABSTRACT Many species of pathogenic fungi deploy the unfolded protein response (UPR) to expand the folding capacity of the endoplasmic reticulum (ER) in proportion to the demand for virulence-related proteins that traffic through the secretory pathway. Although Ca2+ plays a pivotal role in ER functi...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/007980a41c5748d0a0a5bb8f3bb9a8fa |
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