Attenuation of CCl4-induced hepatic fibrosis in mice by vaccinating against TGF-β1.
Transforming growth factor β1 (TGF-β1) is the pivotal pro-fibrogenic cytokine in hepatic fibrosis. Reducing the over-produced expression of TGF-β1 or blocking its signaling pathways is considered to be a promising therapeutic strategy for hepatic fibrosis. In this study, we evaluated the feasibility...
Guardado en:
Autores principales: | Xiaobao Fan, Qiannan Zhang, Shuang Li, Yifei Lv, Houqiang Su, Huiping Jiang, Zhiming Hao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/007d329ef4d04654b1b3b8085e3a0f1c |
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