Attenuation of CCl4-induced hepatic fibrosis in mice by vaccinating against TGF-β1.

Transforming growth factor β1 (TGF-β1) is the pivotal pro-fibrogenic cytokine in hepatic fibrosis. Reducing the over-produced expression of TGF-β1 or blocking its signaling pathways is considered to be a promising therapeutic strategy for hepatic fibrosis. In this study, we evaluated the feasibility...

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Autores principales: Xiaobao Fan, Qiannan Zhang, Shuang Li, Yifei Lv, Houqiang Su, Huiping Jiang, Zhiming Hao
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/007d329ef4d04654b1b3b8085e3a0f1c
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