Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition

Centromere maintenance depends on the persistence of the histone variant CENP-A at the centromeres. Here, the authors characterize the core centromeric nucleosome complex wherein CENP-C confers a stable CENP-A nucleosome conformation and CENP-N fastens CENP-A to the DNA.

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Autores principales: Lucie Y. Guo, Praveen Kumar Allu, Levani Zandarashvili, Kara L. McKinley, Nikolina Sekulic, Jennine M. Dawicki-McKenna, Daniele Fachinetti, Glennis A. Logsdon, Ryan M. Jamiolkowski, Don W. Cleveland, Iain M. Cheeseman, Ben E. Black
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/007ef2a91d124eb6baa7acd0387157c4
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spelling oai:doaj.org-article:007ef2a91d124eb6baa7acd0387157c42021-12-02T17:06:25ZCentromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition10.1038/ncomms157752041-1723https://doaj.org/article/007ef2a91d124eb6baa7acd0387157c42017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15775https://doaj.org/toc/2041-1723Centromere maintenance depends on the persistence of the histone variant CENP-A at the centromeres. Here, the authors characterize the core centromeric nucleosome complex wherein CENP-C confers a stable CENP-A nucleosome conformation and CENP-N fastens CENP-A to the DNA.Lucie Y. GuoPraveen Kumar AlluLevani ZandarashviliKara L. McKinleyNikolina SekulicJennine M. Dawicki-McKennaDaniele FachinettiGlennis A. LogsdonRyan M. JamiolkowskiDon W. ClevelandIain M. CheesemanBen E. BlackNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lucie Y. Guo
Praveen Kumar Allu
Levani Zandarashvili
Kara L. McKinley
Nikolina Sekulic
Jennine M. Dawicki-McKenna
Daniele Fachinetti
Glennis A. Logsdon
Ryan M. Jamiolkowski
Don W. Cleveland
Iain M. Cheeseman
Ben E. Black
Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
description Centromere maintenance depends on the persistence of the histone variant CENP-A at the centromeres. Here, the authors characterize the core centromeric nucleosome complex wherein CENP-C confers a stable CENP-A nucleosome conformation and CENP-N fastens CENP-A to the DNA.
format article
author Lucie Y. Guo
Praveen Kumar Allu
Levani Zandarashvili
Kara L. McKinley
Nikolina Sekulic
Jennine M. Dawicki-McKenna
Daniele Fachinetti
Glennis A. Logsdon
Ryan M. Jamiolkowski
Don W. Cleveland
Iain M. Cheeseman
Ben E. Black
author_facet Lucie Y. Guo
Praveen Kumar Allu
Levani Zandarashvili
Kara L. McKinley
Nikolina Sekulic
Jennine M. Dawicki-McKenna
Daniele Fachinetti
Glennis A. Logsdon
Ryan M. Jamiolkowski
Don W. Cleveland
Iain M. Cheeseman
Ben E. Black
author_sort Lucie Y. Guo
title Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
title_short Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
title_full Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
title_fullStr Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
title_full_unstemmed Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
title_sort centromeres are maintained by fastening cenp-a to dna and directing an arginine anchor-dependent nucleosome transition
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/007ef2a91d124eb6baa7acd0387157c4
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