Endophthalmitis: state of the art

Kamyar Vaziri, Stephen G Schwartz, Krishna Kishor, Harry W Flynn Jr Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: Endophthalmitis is an uncommon diagnosis but can have devastating visual outcomes. Endophthalmitis...

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Autores principales:	Vaziri K, Schwartz SG, Kishor K, Flynn HW Jr
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/008231d77b774750b7844a737cfa12c9
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spelling	oai:doaj.org-article:008231d77b774750b7844a737cfa12c92021-12-02T00:15:58ZEndophthalmitis: state of the art1177-5483https://doaj.org/article/008231d77b774750b7844a737cfa12c92015-01-01T00:00:00Zhttp://www.dovepress.com/endophthalmitis-state-of-the-art-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Kamyar Vaziri, Stephen G Schwartz, Krishna Kishor, Harry W Flynn Jr Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: Endophthalmitis is an uncommon diagnosis but can have devastating visual outcomes. Endophthalmitis may be endogenous or exogenous. Exogenous endophthalmitis is caused by introduction of pathogens through mechanisms such as ocular surgery, open-globe trauma, and intravitreal injections. Endogenous endophthalmitis occurs as a result of hematogenous spread of bacteria or fungi into the eye. These categories of endophthalmitis have different risk factors and causative pathogens, and thus require different diagnostic, prevention, and treatment strategies. Novel diagnostic techniques such as real-time polymerase chain reaction (RT-PCR) have been reported to provide improved diagnostic results over traditional culture techniques and may have a more expanded role in the future. While the role of povidone-iodine in prophylaxis of postoperative endophthalmitis is established, there remains controversy with regard to the effectiveness of other measures, including prophylactic antibiotics. The Endophthalmitis Vitrectomy Study (EVS) has provided us with valuable treatment guidelines. However, these guidelines cannot be directly applied to all categories of endophthalmitis, highlighting the need for continued research into attaining improved treatment outcomes. Keywords: endophthalmitis, exogenous, endogenous, postoperative, intravitreal injectionVaziri KSchwartz SGKishor KFlynn HW JrDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 95-108 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Vaziri K Schwartz SG Kishor K Flynn HW Jr Endophthalmitis: state of the art
description	Kamyar Vaziri, Stephen G Schwartz, Krishna Kishor, Harry W Flynn Jr Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: Endophthalmitis is an uncommon diagnosis but can have devastating visual outcomes. Endophthalmitis may be endogenous or exogenous. Exogenous endophthalmitis is caused by introduction of pathogens through mechanisms such as ocular surgery, open-globe trauma, and intravitreal injections. Endogenous endophthalmitis occurs as a result of hematogenous spread of bacteria or fungi into the eye. These categories of endophthalmitis have different risk factors and causative pathogens, and thus require different diagnostic, prevention, and treatment strategies. Novel diagnostic techniques such as real-time polymerase chain reaction (RT-PCR) have been reported to provide improved diagnostic results over traditional culture techniques and may have a more expanded role in the future. While the role of povidone-iodine in prophylaxis of postoperative endophthalmitis is established, there remains controversy with regard to the effectiveness of other measures, including prophylactic antibiotics. The Endophthalmitis Vitrectomy Study (EVS) has provided us with valuable treatment guidelines. However, these guidelines cannot be directly applied to all categories of endophthalmitis, highlighting the need for continued research into attaining improved treatment outcomes. Keywords: endophthalmitis, exogenous, endogenous, postoperative, intravitreal injection
format	article
author	Vaziri K Schwartz SG Kishor K Flynn HW Jr
author_facet	Vaziri K Schwartz SG Kishor K Flynn HW Jr
author_sort	Vaziri K
title	Endophthalmitis: state of the art
title_short	Endophthalmitis: state of the art
title_full	Endophthalmitis: state of the art
title_fullStr	Endophthalmitis: state of the art
title_full_unstemmed	Endophthalmitis: state of the art
title_sort	endophthalmitis: state of the art
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/008231d77b774750b7844a737cfa12c9
work_keys_str_mv	AT vazirik endophthalmitisstateoftheart AT schwartzsg endophthalmitisstateoftheart AT kishork endophthalmitisstateoftheart AT flynnhwjr endophthalmitisstateoftheart
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Endophthalmitis: state of the art

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