Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination

Viruses expressing tumour antigens can prime and boost anti-tumour immunity but the efficiency of this approach depends on the capacity of the virus to infect the host. Here, the authors show that vaccination with oncolytic viruses co-administered with tumour antigenic peptides is as efficient as an...

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Main Authors:	D. G. Roy, K. Geoffroy, M. Marguerie, S. T. Khan, N. T. Martin, J. Kmiecik, D. Bobbala, A. S. Aitken, C. T. de Souza, K. B. Stephenson, B. D. Lichty, R. C. Auer, D. F. Stojdl, J. C. Bell, M.-C. Bourgeois-Daigneault
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/0087d0d0e932497c868d4c3d99452a6d
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spelling	oai:doaj.org-article:0087d0d0e932497c868d4c3d99452a6d2021-12-02T14:35:46ZAdjuvant oncolytic virotherapy for personalized anti-cancer vaccination10.1038/s41467-021-22929-z2041-1723https://doaj.org/article/0087d0d0e932497c868d4c3d99452a6d2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22929-zhttps://doaj.org/toc/2041-1723Viruses expressing tumour antigens can prime and boost anti-tumour immunity but the efficiency of this approach depends on the capacity of the virus to infect the host. Here, the authors show that vaccination with oncolytic viruses co-administered with tumour antigenic peptides is as efficient as antigen-engineered oncolytic viruses.D. G. RoyK. GeoffroyM. MarguerieS. T. KhanN. T. MartinJ. KmiecikD. BobbalaA. S. AitkenC. T. de SouzaK. B. StephensonB. D. LichtyR. C. AuerD. F. StojdlJ. C. BellM.-C. Bourgeois-DaigneaultNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q D. G. Roy K. Geoffroy M. Marguerie S. T. Khan N. T. Martin J. Kmiecik D. Bobbala A. S. Aitken C. T. de Souza K. B. Stephenson B. D. Lichty R. C. Auer D. F. Stojdl J. C. Bell M.-C. Bourgeois-Daigneault Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
description	Viruses expressing tumour antigens can prime and boost anti-tumour immunity but the efficiency of this approach depends on the capacity of the virus to infect the host. Here, the authors show that vaccination with oncolytic viruses co-administered with tumour antigenic peptides is as efficient as antigen-engineered oncolytic viruses.
format	article
author	D. G. Roy K. Geoffroy M. Marguerie S. T. Khan N. T. Martin J. Kmiecik D. Bobbala A. S. Aitken C. T. de Souza K. B. Stephenson B. D. Lichty R. C. Auer D. F. Stojdl J. C. Bell M.-C. Bourgeois-Daigneault
author_facet	D. G. Roy K. Geoffroy M. Marguerie S. T. Khan N. T. Martin J. Kmiecik D. Bobbala A. S. Aitken C. T. de Souza K. B. Stephenson B. D. Lichty R. C. Auer D. F. Stojdl J. C. Bell M.-C. Bourgeois-Daigneault
author_sort	D. G. Roy
title	Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
title_short	Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
title_full	Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
title_fullStr	Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
title_full_unstemmed	Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
title_sort	adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0087d0d0e932497c868d4c3d99452a6d
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Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination

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