Bimodal sensing of guidance cues in mechanically distinct microenvironments
Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means.
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0089919579e3475c95e212fc5fe23d0a |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0089919579e3475c95e212fc5fe23d0a2021-12-02T16:49:39ZBimodal sensing of guidance cues in mechanically distinct microenvironments10.1038/s41467-018-07290-y2041-1723https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07290-yhttps://doaj.org/toc/2041-1723Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means.Erdem D. TabdanovVikram V. PuramZaw WinAshab AlamgirPatrick W. AlfordPaolo P. ProvenzanoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano Bimodal sensing of guidance cues in mechanically distinct microenvironments |
description |
Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means. |
format |
article |
author |
Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano |
author_facet |
Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano |
author_sort |
Erdem D. Tabdanov |
title |
Bimodal sensing of guidance cues in mechanically distinct microenvironments |
title_short |
Bimodal sensing of guidance cues in mechanically distinct microenvironments |
title_full |
Bimodal sensing of guidance cues in mechanically distinct microenvironments |
title_fullStr |
Bimodal sensing of guidance cues in mechanically distinct microenvironments |
title_full_unstemmed |
Bimodal sensing of guidance cues in mechanically distinct microenvironments |
title_sort |
bimodal sensing of guidance cues in mechanically distinct microenvironments |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a |
work_keys_str_mv |
AT erdemdtabdanov bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT vikramvpuram bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT zawwin bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT ashabalamgir bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT patrickwalford bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT paolopprovenzano bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments |
_version_ |
1718383255203348480 |