Bimodal sensing of guidance cues in mechanically distinct microenvironments

Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means.

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Autores principales:	Erdem D. Tabdanov, Vikram V. Puram, Zaw Win, Ashab Alamgir, Patrick W. Alford, Paolo P. Provenzano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a
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spelling	oai:doaj.org-article:0089919579e3475c95e212fc5fe23d0a2021-12-02T16:49:39ZBimodal sensing of guidance cues in mechanically distinct microenvironments10.1038/s41467-018-07290-y2041-1723https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07290-yhttps://doaj.org/toc/2041-1723Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means.Erdem D. TabdanovVikram V. PuramZaw WinAshab AlamgirPatrick W. AlfordPaolo P. ProvenzanoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano Bimodal sensing of guidance cues in mechanically distinct microenvironments
description	Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and contractility-independent means.
format	article
author	Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano
author_facet	Erdem D. Tabdanov Vikram V. Puram Zaw Win Ashab Alamgir Patrick W. Alford Paolo P. Provenzano
author_sort	Erdem D. Tabdanov
title	Bimodal sensing of guidance cues in mechanically distinct microenvironments
title_short	Bimodal sensing of guidance cues in mechanically distinct microenvironments
title_full	Bimodal sensing of guidance cues in mechanically distinct microenvironments
title_fullStr	Bimodal sensing of guidance cues in mechanically distinct microenvironments
title_full_unstemmed	Bimodal sensing of guidance cues in mechanically distinct microenvironments
title_sort	bimodal sensing of guidance cues in mechanically distinct microenvironments
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a
work_keys_str_mv	AT erdemdtabdanov bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT vikramvpuram bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT zawwin bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT ashabalamgir bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT patrickwalford bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments AT paolopprovenzano bimodalsensingofguidancecuesinmechanicallydistinctmicroenvironments
_version_	1718383255203348480

Bimodal sensing of guidance cues in mechanically distinct microenvironments

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