Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting

Phase Transition Curves (PTCs) describe phase shifts of circadian oscillations due to a stimulus and they are important for studying circadian clock resetting. Here, the authors present a method for high-throughput reconstruction of PTCs using fluorescent live imaging and single-cell analysis.

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Autores principales: Gal Manella, Dan Aizik, Rona Aviram, Marina Golik, Gad Asher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0094d79befcb4111bb26a0917784e7ec
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spelling oai:doaj.org-article:0094d79befcb4111bb26a0917784e7ec2021-12-02T18:37:28ZCirca-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting10.1038/s41467-021-26210-12041-1723https://doaj.org/article/0094d79befcb4111bb26a0917784e7ec2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26210-1https://doaj.org/toc/2041-1723Phase Transition Curves (PTCs) describe phase shifts of circadian oscillations due to a stimulus and they are important for studying circadian clock resetting. Here, the authors present a method for high-throughput reconstruction of PTCs using fluorescent live imaging and single-cell analysis.Gal ManellaDan AizikRona AviramMarina GolikGad AsherNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gal Manella
Dan Aizik
Rona Aviram
Marina Golik
Gad Asher
Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
description Phase Transition Curves (PTCs) describe phase shifts of circadian oscillations due to a stimulus and they are important for studying circadian clock resetting. Here, the authors present a method for high-throughput reconstruction of PTCs using fluorescent live imaging and single-cell analysis.
format article
author Gal Manella
Dan Aizik
Rona Aviram
Marina Golik
Gad Asher
author_facet Gal Manella
Dan Aizik
Rona Aviram
Marina Golik
Gad Asher
author_sort Gal Manella
title Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
title_short Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
title_full Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
title_fullStr Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
title_full_unstemmed Circa-SCOPE: high-throughput live single-cell imaging method for analysis of circadian clock resetting
title_sort circa-scope: high-throughput live single-cell imaging method for analysis of circadian clock resetting
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0094d79befcb4111bb26a0917784e7ec
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AT ronaaviram circascopehighthroughputlivesinglecellimagingmethodforanalysisofcircadianclockresetting
AT marinagolik circascopehighthroughputlivesinglecellimagingmethodforanalysisofcircadianclockresetting
AT gadasher circascopehighthroughputlivesinglecellimagingmethodforanalysisofcircadianclockresetting
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