Pten is necessary for the quiescence and maintenance of adult muscle stem cells

Pten is known to regulate haematopoietic stem cell functions. Here the authors show that Ptenalteration of Notch signalling has stage-specific muscle regenerative functions in muscle stem cells by preventing premature differentiation of quiescent cells and enhancing the self-renewal of activated cel...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Feng Yue, Pengpeng Bi, Chao Wang, Tizhong Shan, Yaohui Nie, Timothy L. Ratliff, Timothy P. Gavin, Shihuan Kuang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/00969596d127462ca70e44a0269cbe23
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:00969596d127462ca70e44a0269cbe23
record_format	dspace
spelling	oai:doaj.org-article:00969596d127462ca70e44a0269cbe232021-12-02T14:42:37ZPten is necessary for the quiescence and maintenance of adult muscle stem cells10.1038/ncomms143282041-1723https://doaj.org/article/00969596d127462ca70e44a0269cbe232017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14328https://doaj.org/toc/2041-1723Pten is known to regulate haematopoietic stem cell functions. Here the authors show that Ptenalteration of Notch signalling has stage-specific muscle regenerative functions in muscle stem cells by preventing premature differentiation of quiescent cells and enhancing the self-renewal of activated cells.Feng YuePengpeng BiChao WangTizhong ShanYaohui NieTimothy L. RatliffTimothy P. GavinShihuan KuangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Feng Yue Pengpeng Bi Chao Wang Tizhong Shan Yaohui Nie Timothy L. Ratliff Timothy P. Gavin Shihuan Kuang Pten is necessary for the quiescence and maintenance of adult muscle stem cells
description	Pten is known to regulate haematopoietic stem cell functions. Here the authors show that Ptenalteration of Notch signalling has stage-specific muscle regenerative functions in muscle stem cells by preventing premature differentiation of quiescent cells and enhancing the self-renewal of activated cells.
format	article
author	Feng Yue Pengpeng Bi Chao Wang Tizhong Shan Yaohui Nie Timothy L. Ratliff Timothy P. Gavin Shihuan Kuang
author_facet	Feng Yue Pengpeng Bi Chao Wang Tizhong Shan Yaohui Nie Timothy L. Ratliff Timothy P. Gavin Shihuan Kuang
author_sort	Feng Yue
title	Pten is necessary for the quiescence and maintenance of adult muscle stem cells
title_short	Pten is necessary for the quiescence and maintenance of adult muscle stem cells
title_full	Pten is necessary for the quiescence and maintenance of adult muscle stem cells
title_fullStr	Pten is necessary for the quiescence and maintenance of adult muscle stem cells
title_full_unstemmed	Pten is necessary for the quiescence and maintenance of adult muscle stem cells
title_sort	pten is necessary for the quiescence and maintenance of adult muscle stem cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/00969596d127462ca70e44a0269cbe23
work_keys_str_mv	AT fengyue ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT pengpengbi ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT chaowang ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT tizhongshan ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT yaohuinie ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT timothylratliff ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT timothypgavin ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells AT shihuankuang ptenisnecessaryforthequiescenceandmaintenanceofadultmusclestemcells
_version_	1718389609842343936

Pten is necessary for the quiescence and maintenance of adult muscle stem cells

Ejemplares similares