Pten is necessary for the quiescence and maintenance of adult muscle stem cells

Pten is necessary for the quiescence and maintenance of adult muscle stem cells

Pten is known to regulate haematopoietic stem cell functions. Here the authors show that Ptenalteration of Notch signalling has stage-specific muscle regenerative functions in muscle stem cells by preventing premature differentiation of quiescent cells and enhancing the self-renewal of activated cel...

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Autores principales: Feng Yue, Pengpeng Bi, Chao Wang, Tizhong Shan, Yaohui Nie, Timothy L. Ratliff, Timothy P. Gavin, Shihuan Kuang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/00969596d127462ca70e44a0269cbe23
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