The <i>Toxoplasma</i> Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
Inflammation in the brain caused by infections lead to seizures and other neurological symptoms. But the microbial products that induce seizures as well as the host pathways downstream of these factors are largely unknown.
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American Society for Microbiology
2021
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oai:doaj.org-article:009cc65add2f48c0955f42782c8338422021-11-03T21:15:04Z The <i>Toxoplasma</i> Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain 2150-751110.1128/mBio.01331-21https://doaj.org/article/009cc65add2f48c0955f42782c8338422021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01331-21https://doaj.org/toc/2150-7511 Inflammation in the brain caused by infections lead to seizures and other neurological symptoms. But the microbial products that induce seizures as well as the host pathways downstream of these factors are largely unknown.Taylor G. GlausenGabriela L. CarrilloRichard M. JinJon P. BoyleJeroen P. J. SaeijElizabeth A. WohlfertMichael A. FoxIra J. BladerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Taylor G. Glausen Gabriela L. Carrillo Richard M. Jin Jon P. Boyle Jeroen P. J. Saeij Elizabeth A. Wohlfert Michael A. Fox Ira J. Blader The <i>Toxoplasma</i> Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain |
| description |
Inflammation in the brain caused by infections lead to seizures and other neurological symptoms. But the microbial products that induce seizures as well as the host pathways downstream of these factors are largely unknown. |
| format |
article |
| author |
Taylor G. Glausen Gabriela L. Carrillo Richard M. Jin Jon P. Boyle Jeroen P. J. Saeij Elizabeth A. Wohlfert Michael A. Fox Ira J. Blader |
| author_facet |
Taylor G. Glausen Gabriela L. Carrillo Richard M. Jin Jon P. Boyle Jeroen P. J. Saeij Elizabeth A. Wohlfert Michael A. Fox Ira J. Blader |
| author_sort |
Taylor G. Glausen |
| title |
The
<i>Toxoplasma</i>
Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
|
| title_short |
The
<i>Toxoplasma</i>
Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
|
| title_full |
The
<i>Toxoplasma</i>
Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
|
| title_fullStr |
The
<i>Toxoplasma</i>
Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
|
| title_full_unstemmed |
The
<i>Toxoplasma</i>
Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain
|
| title_sort |
the
<i>toxoplasma</i>
polymorphic effector gra15 mediates seizure induction by modulating interleukin-1 signaling in the brain |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/009cc65add2f48c0955f42782c833842 |
| work_keys_str_mv |
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