High BTLA Expression Likely Contributes to Contraction of the Regulatory T Cell Subset in Lupus Disease

B and T lymphocyte attenuator (BTLA) is a co-inhibitory receptor that is expressed by lymphoid cells and regulates the immune response. Consistent with an inhibitory role for BTLA, the disease is exacerbated in BTLA-deficient lupus mice. We recently demonstrated that the BTLA pathway is altered in C...

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Autores principales: Lucie Aubergeon, Matthieu Sawaf, Renaud Felten, Jacques-Eric Gottenberg, Hélène Dumortier, Fanny Monneaux
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/00a13d67ceb24112934b1ef0290bb93e
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