High BTLA Expression Likely Contributes to Contraction of the Regulatory T Cell Subset in Lupus Disease
B and T lymphocyte attenuator (BTLA) is a co-inhibitory receptor that is expressed by lymphoid cells and regulates the immune response. Consistent with an inhibitory role for BTLA, the disease is exacerbated in BTLA-deficient lupus mice. We recently demonstrated that the BTLA pathway is altered in C...
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Autores principales: | Lucie Aubergeon, Matthieu Sawaf, Renaud Felten, Jacques-Eric Gottenberg, Hélène Dumortier, Fanny Monneaux |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://doaj.org/article/00a13d67ceb24112934b1ef0290bb93e |
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