Study of the effect of Lithium Chloride on memory and behaviour in rat

Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into...

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Autores principales: A Arzi, M Moustofi
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2000
Materias:
rat
R
Acceso en línea:https://doaj.org/article/00add6791b7340909e67abd109c893e2
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Sumario:Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into two groups of fifty, one group received lithium chloride subcutaneously, where as the other group received normal saline as control. Two parameters: 1) Entrance direction of rats to each T-maze apparatus 2) Time taken by rats to reach the target box containing food, through T-maze shaped apparatus were studied. Findings: Statistical analysis of results indicates that the rat in the test group required a longer period of time to reach the target box, and also it had difficulty in choosing the box as compared with those in control group. Conclusion: On the basis of results, it might be indicated that lithium chloride has a negative effect on memory and behavior in rat.