Study of the effect of Lithium Chloride on memory and behaviour in rat

Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into...

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Autores principales: A Arzi, M Moustofi
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2000
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Acceso en línea:https://doaj.org/article/00add6791b7340909e67abd109c893e2
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spelling oai:doaj.org-article:00add6791b7340909e67abd109c893e22021-11-10T09:22:13ZStudy of the effect of Lithium Chloride on memory and behaviour in rat1561-41072251-7170https://doaj.org/article/00add6791b7340909e67abd109c893e22000-07-01T00:00:00Zhttp://jbums.org/article-1-2897-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into two groups of fifty, one group received lithium chloride subcutaneously, where as the other group received normal saline as control. Two parameters: 1) Entrance direction of rats to each T-maze apparatus 2) Time taken by rats to reach the target box containing food, through T-maze shaped apparatus were studied. Findings: Statistical analysis of results indicates that the rat in the test group required a longer period of time to reach the target box, and also it had difficulty in choosing the box as compared with those in control group. Conclusion: On the basis of results, it might be indicated that lithium chloride has a negative effect on memory and behavior in rat.A ArziM MoustofiBabol University of Medical Sciencesarticlelithium chloridememorybehaviourratMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 2, Iss 3, Pp 7-11 (2000)
institution DOAJ
collection DOAJ
language EN
FA
topic lithium chloride
memory
behaviour
rat
Medicine
R
Medicine (General)
R5-920
spellingShingle lithium chloride
memory
behaviour
rat
Medicine
R
Medicine (General)
R5-920
A Arzi
M Moustofi
Study of the effect of Lithium Chloride on memory and behaviour in rat
description Objective: In this study lithium chloride was used in order to find out its effect on memory and behavior of rats. Methods: In this experiment T-maze shaped apparatus was used. The animals used in this study were male rats with approximate weight of 120-150 g. The animals were randomly divided into two groups of fifty, one group received lithium chloride subcutaneously, where as the other group received normal saline as control. Two parameters: 1) Entrance direction of rats to each T-maze apparatus 2) Time taken by rats to reach the target box containing food, through T-maze shaped apparatus were studied. Findings: Statistical analysis of results indicates that the rat in the test group required a longer period of time to reach the target box, and also it had difficulty in choosing the box as compared with those in control group. Conclusion: On the basis of results, it might be indicated that lithium chloride has a negative effect on memory and behavior in rat.
format article
author A Arzi
M Moustofi
author_facet A Arzi
M Moustofi
author_sort A Arzi
title Study of the effect of Lithium Chloride on memory and behaviour in rat
title_short Study of the effect of Lithium Chloride on memory and behaviour in rat
title_full Study of the effect of Lithium Chloride on memory and behaviour in rat
title_fullStr Study of the effect of Lithium Chloride on memory and behaviour in rat
title_full_unstemmed Study of the effect of Lithium Chloride on memory and behaviour in rat
title_sort study of the effect of lithium chloride on memory and behaviour in rat
publisher Babol University of Medical Sciences
publishDate 2000
url https://doaj.org/article/00add6791b7340909e67abd109c893e2
work_keys_str_mv AT aarzi studyoftheeffectoflithiumchlorideonmemoryandbehaviourinrat
AT mmoustofi studyoftheeffectoflithiumchlorideonmemoryandbehaviourinrat
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