Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Male pattern baldness (MPB) is a polygenic trait that affects the majority of European men. Here, Yap et al. estimate heritability, partitioned by autosomes and the X-chromosome, of MPB in the UK Biobank cohort, perform GWAS for MPB and find genetic correlation with other sex-specific traits.

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Autores principales:	Chloe X. Yap, Julia Sidorenko, Yang Wu, Kathryn E. Kemper, Jian Yang, Naomi R. Wray, Matthew R. Robinson, Peter M. Visscher
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/00b21185b32e4c10bc5428bbcfe6ff83
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spelling	oai:doaj.org-article:00b21185b32e4c10bc5428bbcfe6ff832021-12-02T17:32:31ZDissection of genetic variation and evidence for pleiotropy in male pattern baldness10.1038/s41467-018-07862-y2041-1723https://doaj.org/article/00b21185b32e4c10bc5428bbcfe6ff832018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07862-yhttps://doaj.org/toc/2041-1723Male pattern baldness (MPB) is a polygenic trait that affects the majority of European men. Here, Yap et al. estimate heritability, partitioned by autosomes and the X-chromosome, of MPB in the UK Biobank cohort, perform GWAS for MPB and find genetic correlation with other sex-specific traits.Chloe X. YapJulia SidorenkoYang WuKathryn E. KemperJian YangNaomi R. WrayMatthew R. RobinsonPeter M. VisscherNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chloe X. Yap Julia Sidorenko Yang Wu Kathryn E. Kemper Jian Yang Naomi R. Wray Matthew R. Robinson Peter M. Visscher Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
description	Male pattern baldness (MPB) is a polygenic trait that affects the majority of European men. Here, Yap et al. estimate heritability, partitioned by autosomes and the X-chromosome, of MPB in the UK Biobank cohort, perform GWAS for MPB and find genetic correlation with other sex-specific traits.
format	article
author	Chloe X. Yap Julia Sidorenko Yang Wu Kathryn E. Kemper Jian Yang Naomi R. Wray Matthew R. Robinson Peter M. Visscher
author_facet	Chloe X. Yap Julia Sidorenko Yang Wu Kathryn E. Kemper Jian Yang Naomi R. Wray Matthew R. Robinson Peter M. Visscher
author_sort	Chloe X. Yap
title	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
title_short	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
title_full	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
title_fullStr	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
title_full_unstemmed	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
title_sort	dissection of genetic variation and evidence for pleiotropy in male pattern baldness
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/00b21185b32e4c10bc5428bbcfe6ff83
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Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

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