Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases

Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases

Abstract IKKα and IKKβ are essential kinases for activating NF-κB transcription factors that regulate cellular differentiation and inflammation. By virtue of their small size, chemokines support the crosstalk between cartilage and other joint compartments and contribute to immune cell chemotaxis in...

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Autores principales: Eleonora Olivotto, Manuela Minguzzi, Stefania D’Adamo, Annalisa Astolfi, Spartaco Santi, Mariagrazia Uguccioni, Kenneth B. Marcu, Rosa Maria Borzì
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/00c09dde5874444aa957f124a45639f9
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